1 Result for "

935685-90-8

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "935685-90-8" in MCE Product Catalog:

Cat. No.: HY-W565924
CAS No.: 935685-90-8
Target:  

mGluR ERK

Research Areas:  

Neurological Disease

STX107 is a metabotropic glutamate 5 (mGlu5) receptor negative allosteric modulator (NAM) with a pKi of 8.32. STX107 inhibits glutamate-induced Ca 2+ mobilization, IP1 accumulation, and ERK1/2 phosphorylation. STX107 also inhibits glutamate-induced mGlu5 internalization .
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