935685-90-8

STX107 Chemical Structure
935685-90-8

Chemical Structure

STX107

  • CAS No.: 935685-90-8
  • Formula:C18H10FN3S
  • Molecular Weight:319.36

IUPAC Name: 3-fluoro-5-(5-((2-methylthiazol-4-yl)ethynyl)pyridin-2-yl)benzonitrile

InChIKey: SYOSUEIMOYEGKU-UHFFFAOYSA-N

SMILES: N#CC1=CC(F)=CC(C2=NC=C(C=C2)C#CC3=CSC(C)=N3)=C1

Biological Activity: STX107 is a metabotropic glutamate 5 (mGlu5) receptor negative allosteric modulator (NAM) with a pKi of 8.32. STX107 inhibits glutamate-induced Ca2+ mobilization, IP1 accumulation, and ERK1/2 phosphorylation. STX107 also inhibits glutamate-induced mGlu5 internalization[1].

Cat. No. Product Name Purity Description Pricing
HY-W565924 		STX107 STX107 is a metabotropic glutamate 5 (mGlu5) receptor negative allosteric modulator (NAM) with a pKi of 8.32. STX107 inhibits glutamate-induced Ca2+ mobilization, IP1 accumulation, and ERK1/2 phosphorylation. STX107 also inhibits glutamate-induced mGlu5 internalization.
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