2 Results for "

943540-75-8

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "943540-75-8" in MCE Product Catalog:

6
6 Cited Publications
Cat. No.: HY-50683
CAS No.: 943540-75-8
Target:  

c-Met/HGFR

Research Areas:  

Metabolic Disease Cancer

JNJ-38877605 is an orally active ATP-competitive inhibitor of c-Met with an IC50 of 4 nM, 600-fold selective for c-Met than 200 other tyrosine and serine-threonine kinases . JNJ-38877605 inhibits c-Met phosphorylation and regulates lipid accumulation. JNJ-38877605 can be used for tumor and metabolic disease reseach .
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Cat. No.: HY-50683S
CAS No.: 1936472-36-4
JNJ-38877605-d1 (compound DO-2) is a highly selective MNNG HOS transforming (MET) inhibitor. JNJ-38877605-d1 is thought to diminish the formation of the Aldehyde Oxidase 1 inactive metabolite M3 .
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