1 Result for "

956103-79-0

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "956103-79-0" in MCE Product Catalog:

Cochinchinenin C
Cochinchinenin C
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Cat. No.: HY-N2452
CAS No.: 956103-79-0
Category:  

other families Metabolic Disease Phenols Polyphenols Plants Disease Research Fields

Target:  

GLP Receptor

Cochinchinenin C is a GLP-1R agonist that binds to the extracellular domain of the receptor via hydrophobic interactions and hydrogen bonds, and promotes glucose-dependent insulin secretion from pancreatic β-cells. Cochinchinenin C also increases intracellular cAMP and ATP levels. At low concentrations, Cochinchinenin C binds to human serum albumin, alters its microenvironment, and induces dominant static fluorescence quenching. Cochinchinenin C shows almost no cytotoxicity to pancreatic β-cells, and exerts a synergistic effect with Loureirin A (HY-N1505) when binding to human serum albumin. Cochinchinenin C has been widely used in studies of type 2 diabetes, Helicobacter pylori infection, thrombotic diseases, and other conditions .
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