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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
119 Results for "
A11
" in MedChemExpress (MCE) Product Catalog:
Products (119)
119 Results for "A11" in MCE Product Catalog:
13
1
1
1 Cited Publications
Cat. No.: HY-P702444
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Cystine/glutamate transporter; Amino acid transport system xc-; Calcium channel blocker resistance protein CCBR1; Solute carrier family 7 member 11; xCT
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Cat. No.: HY-170333
CAS No.: 2996998-09-3
Synonyms: CICL1
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Lipid A-11 (Compound A-11) (CICL1) is an ionizable cationic lipid. Lipid A-11 can be used to prepare lipid nanoparticles. Lipid A-11 can be used in research involving T cell-targeted transfection .
Cat. No.: HY-P10412
CAS No.: 2412926-30-6
Synonyms: ANXA1-derived 11 amino acid-long peptide
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SLC7A11-IN-1 is a potent solute carrier family 7 member 11 (SLC7A11, xCT) inhibitor. SLC7A11-IN-1 shows antiproliferative activity. SLC7A11-IN-1 inhibits cell invasion and metastasis. SLC7A11-IN-1 induces Apoptosis and cell cycle arrest at S-phase. SLC7A11-IN-1 shows anti-tumor activity .
Cat. No.: HY-P10412A
Synonyms: ANXA1-derived 11 amino acid-long peptide acetate
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A11 (ANXA1-derived 11 amino acid-long peptide) acetate is a ANXA1-EphA2 interaction-blocking peptide. A11 acetate reduces ANXA1 bound to EphA2 and increases Cbl (the E3 ubiquitin ligase of EphA2) bound to EphA2. A11 acetate inhibits the proliferation, migration and invasion of nasopharyngeal carcinoma cells. A11 acetate inhibits angiogenesis. A11 acetate can be used in studies related to nasopharyngeal carcinoma .
Synonyms: XMH95
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NSC260594 induces Apoptosis. NSC260594 binds the shallow groove of the Mcl-1 protein, and inhibits Mcl-1 expression through down-regulation of Wnt signaling proteins. NSC260594 can also recognize G9-G10-A11-G12 RNA tetraloop of HIV and prevent the binding of the Gag protein within the 5’-UTR. NSC260594 inhibits tumor growth, and can be used for research of Triple-negative breast cancers (TNBCs) .
Cat. No.: HY-P10664
CAS No.: 147138-29-2
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Cat. No.: HY-169056
CAS No.: 14668-59-8
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SLC7A11-IN-2 (Compound 1) is an SLC7A11/xCT inhibitor. SLC7A11-IN-2 induces cell death in HeLa cells by lowering intracellular glutathione levels and increasing oxidative stress, thereby disrupting the oxidative balance within the cells, with an IC50 value of 10.23 μM. Molecular dynamics simulation analysis indicates that SLC7A11-IN-2 has a stronger binding affinity to SLC7A11 compared to Erastin (HY-15763). SLC7A11-IN-2 can be utilized in research within the field of cervical cancer .
Cat. No.: HY-RS13325
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SLC7A11 Human Pre-designed siRNA Set A contains three designed siRNAs for SLC7A11 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-N3778
CAS No.: 89020-11-1
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Cat. No.: HY-RS13091
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SLC25A11 Human Pre-designed siRNA Set A contains three designed siRNAs for SLC25A11 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-178040
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Insecticidal agent 26 (Compound A11), a spiro insecticidal agent, is a dual-functional inhibitor of pest Acetyl-CoA carboxylase (ACC) and Pyruvate carboxylase (PC). Insecticidal agent 26 has potent insecticidal activity against Sogatella furcifera with a LC50 of 11.0 μg/mL, with significant biosafety to bees. Insecticidal agent 26 can be used for management of white-backed planthoppers (WBPs) .
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CYP4A11/CYP4F2-IN-1 is a potent dual inhibitor of cytochrome P450 (CYP) 4A11 and CYP4F2, with IC50s of 19 nM and 17 nM, respectively. CYP4A11/CYP4F2-IN-1 has potential for the research of renal diseases .
Cat. No.: HY-W653776
CAS No.: 1338549-02-2
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(6a,11β)-11,20-Dihydroxy-6-methyl-3-oxopregna-1,4,17(20)-trien-21-al is a Methylprednisolon (HY-B0260) impurity.
Cat. No.: HY-149452
CAS No.: 2758867-71-7
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SJ1008066 is a MAGE-A11 inhibitor with anIC50 of 0.13 μM. SJ 1008066 binds to the MAGE homology domain (MHD) and disrupts MAGE-A11:PCF11 interaction .
Cat. No.: HY-P5482
CAS No.: 216862-59-8
Cat. No.: HY-P990179
Research Areas:
Cat. No.: HY-160589
CAS No.: 2626945-23-9
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Nav1.8-IN-8 (Compound A11) is a Nav1.8 channel inhibitor. Nav1.8-IN-8 may prevent associated diseases mediated by sodium ion channels (NaV) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
