CYP4A11/CYP4F2-IN-1
Based on 1 Customer Validation
CYP4A11/CYP4F2-IN-1 is a potent dual inhibitor of cytochrome P450 (CYP) 4A11 and CYP4F2, with IC50s of 19 nM and 17 nM, respectively. CYP4A11/CYP4F2-IN-1 has potential for the research of renal diseases.
For research use only. We do not sell to patients.
- Purity: 99.82%
- CAS No.: 502654-40-2
- Formula: C15H15N3OS
- Molecular Weight:285.36
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Bioactive Compound Library Max
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Biological Activity
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CYP4A11 19 nM (IC50) |
CYP4F2 17 nM (IC50) |
CYP4A11/CYP4F2-IN-1 (compound 2) inhibits 20-Hydroxyeicosatetraenoic acid (20-HETE) production from arachidonic acid in human renal microsomes, with an IC50 of 4.2 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 502654-40-2
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Appearance Solid
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Molecular Weight 285.36
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Formula C15H15N3OS
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Color White to off-white
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SMILES
CC1=C(SC=N1)CCOC2=CC=C(C=C2)C3=CC=NN3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 125 mg/mL (438.04 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.5043 mL | 17.5217 mL | 35.0435 mL | 87.6086 mL |
| 5 mM | 0.7009 mL | 3.5043 mL | 7.0087 mL | 17.5217 mL | |
| 10 mM | 0.3504 mL | 1.7522 mL | 3.5043 mL | 8.7609 mL | |
| 15 mM | 0.2336 mL | 1.1681 mL | 2.3362 mL | 5.8406 mL | |
| 20 mM | 0.1752 mL | 0.8761 mL | 1.7522 mL | 4.3804 mL | |
| 25 mM | 0.1402 mL | 0.7009 mL | 1.4017 mL | 3.5043 mL | |
| 30 mM | 0.1168 mL | 0.5841 mL | 1.1681 mL | 2.9203 mL | |
| 40 mM | 0.0876 mL | 0.4380 mL | 0.8761 mL | 2.1902 mL | |
| 50 mM | 0.0701 mL | 0.3504 mL | 0.7009 mL | 1.7522 mL | |
| 60 mM | 0.0584 mL | 0.2920 mL | 0.5841 mL | 1.4601 mL | |
| 80 mM | 0.0438 mL | 0.2190 mL | 0.4380 mL | 1.0951 mL | |
| 100 mM | 0.0350 mL | 0.1752 mL | 0.3504 mL | 0.8761 mL |
CYP4A11/CYP4F2-IN-1 Related Classifications
HY-151809 Related Classifications
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