906718-66-9
Chemical Structure
NSC260594
Synonym(s): XMH95
- CAS No.: 906718-66-9
- Formula:C29H24N6O3
- Molecular Weight:504.54
IUPAC Name: (E)-4-((1-methyl-6-nitroquinolin-4(1H)-ylidene)amino)-N-(4-((1-methylpyridin-4(1H)-ylidene)amino)phenyl)benzamide
InChIKey: SDVVSJQTYKFAFR-TVKQRKNISA-N
SMILES: O=C(NC1=CC=C(/N=C2C=CN(C)C=C\2)C=C1)C3=CC=C(/N=C4C=CN(C)C5=C\4C=C([N+]([O-])=O)C=C5)C=C3
Biological Activity: NSC260594 induces Apoptosis. NSC260594 binds the shallow groove of the Mcl-1 protein, and inhibits Mcl-1 expression through down-regulation of Wnt signaling proteins. NSC260594 can also recognize G9-G10-A11-G12 RNA tetraloop of HIV and prevent the binding of the Gag protein within the 5’-UTR. NSC260594 inhibits tumor growth, and can be used for research of Triple-negative breast cancers (TNBCs)[1].
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NSC260594 | 97.50% | NSC260594 induces Apoptosis. NSC260594 binds the shallow groove of the Mcl-1 protein, and inhibits Mcl-1 expression through down-regulation of Wnt signaling proteins. NSC260594 can also recognize G9-G10-A11-G12 RNA tetraloop of HIV and prevent the binding of the Gag protein within the 5’-UTR. NSC260594 inhibits tumor growth, and can be used for research of Triple-negative breast cancers (TNBCs). | ||||||||||||||||||||
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Keywords
