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Cat. No.: HY-154821

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DRI-C21041

DRI-C21041 is a CD40/CD40L interaction inhibitor, with an IC₅₀ of 0.31 μM. DRI-C21041 inhibits the immune response induced by alloantigen.

For research use only. We do not sell to patients.

CAS No.: 2101765-78-8
Formula: C₃₀H₂₁N₃O₇S
Molecular Weight:567.57

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

DRI-C21041 Chemical Structure

CAS No.: 2101765-78-8

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Sample (0.1mg)

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(In Japan)

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Bioz

Biological Activity

Description

DRI-C21041 is a CD40/CD40L interaction inhibitor, with an IC₅₀ of 0.31 μM. DRI-C21041 inhibits the immune response induced by alloantigen^[1].

IC₅₀ & Target^[1]

CD40L

0.31 μM (IC₅₀)

All TNF Receptor Isoforms :

In Vitro

DRI-C21041 inhibits CD40L-induced B-cell activation, proliferation, and the activation of NF-κB^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2101765-78-8
Molecular Weight 567.57
Formula C₃₀H₂₁N₃O₇S
SMILES

O=S(C1=C2C(NC(C3=CC=C(C4=CC=C(NC(C5=CC=C([N+]([O-])=O)C=C5)=O)C=C4)C=C3)=O)=CC=CC2=CC=C1)(O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Lu H, et, al. Recent advances in the development of protein-protein interactions modulators: mechanisms and clinical trials. Signal Transduct Target Ther. 2020 Sep 23;5(1):213. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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