92 Results for "

ANXA

" in MedChemExpress (MCE) Product Catalog:
Products (92)

92 Results for "ANXA" in MCE Product Catalog:

20
20 Publications Verification
Cat. No.: HY-141644
CAS No.: 2765218-56-0
Purity:  99.10%
Target:  

Annexin A YAP

Research Areas:  

Inflammation/Immunology

PY-60 is a robust and specific activator of YAP transcriptional activity that targets annexin A2 (ANXA2) with a Kd of 1.4 µM. PY-60 directly binds to ANXA2 and antagonizes its normal cellular function of repressing YAP activity .
loading...
    loading...
8
8 Cited Publications
Cat. No.: HY-P2333
CAS No.: 533902-29-3
Target:  

Annexin A

Research Areas:  

Cardiovascular Disease

LCKLSL is a N-terminal hexapeptide and a competitive annexin A2 (AnxA2) inhibitor. LCKLSL potently inhibits the binding of tissue plasminogen activator (tPA) to AnxA2. LCKLSL also inhibits the generation of plasmin and has anti-angiogenic roles .
loading...
    loading...
8
8 Cited Publications
Cat. No.: HY-P2333A
Target:  

Annexin A

Research Areas:  

Cardiovascular Disease

LCKLSL hydrochloride is a N-terminal hexapeptide and a competitive annexin A2 (AnxA2) inhibitor. LCKLSL hydrochloride potently inhibits the binding of tissue plasminogen activator (tPA) to AnxA2. LCKLSL hydrochloride also inhibits the generation of plasmin and has anti-angiogenic roles .
loading...
    loading...
3
3 Cited Publications
Cat. No.: HY-P7515
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ANXA2; Annexin-2; Prev. ANX2L4; PAP-IV; Prev. CAL1H; P36; Prev. LPC2D; Epididymis Secretory Sperm Binding Protein; Prev. ANX2; Epididymis Secretory Protein Li 270; Annexin II; Calpactin I Heavy Polypeptide; LIP2; Chromobindin 8; Placental Anticoagulant Pr
Species:  
Source:  
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-P7512
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ANXA1; Annexin-1; Prev. ANX1; Annexin I (Lipocortin I); Prev. LPC1; ANXA1 Protein; Phospholipase A2 Inhibitory Protein; Lipocortin I; Chromobindin-9; Annexin I; Calpactin II; Annexin; Calpactin-2; P35; Annexin A1; Epididymis Secretory Sperm Binding Protei
Species:  
Source:  
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-P72078
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ANXA1; Annexin-1; Prev. ANX1; Annexin I (Lipocortin I); Prev. LPC1; ANXA1 Protein; Phospholipase A2 Inhibitory Protein; Lipocortin I; Chromobindin-9; Annexin I; Calpactin II; Annexin; Calpactin-2; P35; Annexin A1; Epididymis Secretory Sperm Binding Protei
Species:  
Source:  
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-125355
CAS No.: 1802997-81-4
Purity:  98.26%
Target:  

Apoptosis Annexin A

Research Areas:  

Cancer

SEC induces activation of ANXA7 GTPase via the AMPK/mTORC1/STAT3 signaling pathway. SEC selectively promotes apoptosis in cancer cells, expressing a high level of ITGB4 by inducing ITGB4 nuclear translocation .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P75505
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ANXA8; Annexin-8; Prev. ANX8; CH17-360D5.2; Vascular Anticoagulant-Beta; Annexin; Annexin VIII; Annexin A8; VAC-Beta
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-P10412
CAS No.: 2412926-30-6
Synonyms: ANXA1-derived 11 amino acid-long peptide
Research Areas:  

Cancer

A11 (ANXA1-derived 11 amino acid-long peptide) is a ANXA1-EphA2 interaction-blocking peptide. A11 reduces ANXA1 bound to EphA2 and increases Cbl (the E3 ubiquitin ligase of EphA2) bound to EphA2. A11 inhibits the proliferation, migration and invasion of nasopharyngeal carcinoma cells. A11 inhibits angiogenesis. A11 can be used in studies related to nasopharyngeal carcinoma .
loading...
    loading...
Cat. No.: HY-P10275
Target:  

Apoptosis

Research Areas:  

Neurological Disease

Tat-NTS peptide is a cell-penetrating peptide with neuroprotective effects. Tat-NTS peptide can specifically inhibit the nuclear translocation of ANXA1 and reduce neuronal apoptosis in ischemic areas. Moreover, Tat-NTS peptide can reduce the volume of cerebral ischemic infarction and can be used in the research of ischemic stroke .
loading...
    loading...
Cat. No.: HY-115635
CAS No.: 2309172-24-3
Target:  

Annexin A

Research Areas:  

Others

ABO hydrochloride is a potent modulator of ANXA7 as ABO binds to Thr286 of ANXA7 and inhibits its phosphorylation. ABO promotes autophagy via elevation of ANXA7 and triggering ANXA7 subcellular redistribution .
loading...
    loading...
Cat. No.: HY-RS00757
Research Areas:  

Others

ANXA1 Human Pre-designed siRNA Set A contains three designed siRNAs for ANXA1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
Cat. No.: HY-168950
Target:  

Annexin A

Research Areas:  

Cancer

ANXA3 degrader 1 (Compound 18a5) is a highly selective ANXA3 degrader with cancer cell inhibition activity. ANXA3 degrader 1 displays excellent inhibitory effect in a triple-negative breast cancer (TNBC) tumor xenograft model (TGI=96%) .
loading...
    loading...
Cat. No.: HY-RS00761
Research Areas:  

Others

ANXA2 Human Pre-designed siRNA Set A contains three designed siRNAs for ANXA2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
Cat. No.: HY-176548
CAS No.: 2765218-57-1
Target:  

YAP Annexin A

Research Areas:  

Inflammation/Immunology

PY-PAP is a photoactivatable affinity probe and a derivative of PY-60 (HY-141644). PY-PAP retains the cellular function of activating YAP transcriptional activity. In 293A cells, PY-PAP can label cathepsin D (CTSD) and annexin A2 (ANXA2) through ultraviolet crosslinking and click reactions. PY-PAP plays a key role in identifying ANXA2 as the specific target of PY-60 .
loading...
    loading...
Cat. No.: HY-169212
CAS No.: 445238-07-3
Research Areas:  

Cancer

I194496 is a potent cystathionine γ-lyase (CSE) inhibitor, with an IC50 of 0.79 mM. I194496 can inhibit the growth of human TNBC cells via the dual targeting PI3K/Akt and Ras/Raf/ERK pathway and suppress the metastasis of human TNBC cells via down-regulating Anxa2/STAT3 and VEGF/FAK/Paxillin signaling pathways .
loading...
    loading...
Cat. No.: HY-P10412A
Synonyms: ANXA1-derived 11 amino acid-long peptide acetate
Research Areas:  

Cancer

A11 (ANXA1-derived 11 amino acid-long peptide) acetate is a ANXA1-EphA2 interaction-blocking peptide. A11 acetate reduces ANXA1 bound to EphA2 and increases Cbl (the E3 ubiquitin ligase of EphA2) bound to EphA2. A11 acetate inhibits the proliferation, migration and invasion of nasopharyngeal carcinoma cells. A11 acetate inhibits angiogenesis. A11 acetate can be used in studies related to nasopharyngeal carcinoma .
loading...
    loading...
Cat. No.: HY-RS00759
Research Areas:  

Others

ANXA11 Human Pre-designed siRNA Set A contains three designed siRNAs for ANXA11 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Components

ANXA11 siRNA-1: 5 nmol (HPLC)

ANXA11 siRNA-2: 5 nmol (HPLC)

ANXA11 siRNA-3: 5 nmol (HPLC)

siRNA Negative Control: 5 nmol (HPLC)

FAM-labeled siRNA Negative Control: 5 nmol (HPLC)

GAPDH siRNA Positive Control: 5 nmol (HPLC)

loading...
    loading...
Cat. No.: HY-RS00763
Research Areas:  

Others

ANXA3 Human Pre-designed siRNA Set A contains three designed siRNAs for ANXA3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
Cat. No.: HY-RS16647
Research Areas:  

Others

Anxa1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Anxa1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...