2765218-56-0
2765218-56-0
Chemical Structure
PY-60
- CAS No.: 2765218-56-0
- Formula:C16H15N3O2S
- Molecular Weight:313.37
IUPAC Name: 5-phenyl-N-(3-(thiazol-2-yl)propyl)isoxazole-3-carboxamide
InChIKey: UFASECSYKSMYET-UHFFFAOYSA-N
SMILES: O=C(C1=NOC(C2=CC=CC=C2)=C1)NCCCC3=NC=CS3
Biological Activity: PY-60 is a robust and specific activator of YAP transcriptional activity that targets annexin A2 (ANXA2) with a Kd of 1.4 µM. PY-60 directly binds to ANXA2 and antagonizes its normal cellular function of repressing YAP activity[1].
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PY-60 | 99.42% | PY-60 is a robust and specific activator of YAP transcriptional activity that targets annexin A2 (ANXA2) with a Kd of 1.4 µM. PY-60 directly binds to ANXA2 and antagonizes its normal cellular function of repressing YAP activity. | ||||||||||||||||||||
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References
Keywords
