1802997-81-4
1802997-81-4
Chemical Structure
SEC
- CAS No.: 1802997-81-4
- Formula:C22H23ClN2O5
- Molecular Weight:430.88
IUPAC Name: ethyl (S)-1-(3-(4-chlorophenoxy)-2-hydroxypropyl)-3-(4-methoxyphenyl)-1H-pyrazole-5-carboxylate
InChIKey: OFKGGSVHXHMDDN-KRWDZBQOSA-N
SMILES: O=C(OCC)C1=CC(C2=CC=C(C=C2)OC)=NN1C[C@@H](COC3=CC=C(C=C3)Cl)O
Biological Activity: SEC induces activation of ANXA7 GTPase via the AMPK/mTORC1/STAT3 signaling pathway. SEC selectively promotes apoptosis in cancer cells, expressing a high level of ITGB4 by inducing ITGB4 nuclear translocation[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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SEC | 98.26% | SEC induces activation of ANXA7 GTPase via the AMPK/mTORC1/STAT3 signaling pathway. SEC selectively promotes apoptosis in cancer cells, expressing a high level of ITGB4 by inducing ITGB4 nuclear translocation. | ||||||||||||||||||||
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References
- [1]. ShuYan Liu, et al. SEC-induced Activation of ANXA7 GTPase Suppresses Prostate Cancer Metastasis. Cancer Lett. 2018 Mar 1;416:11-23. [Content Brief]
- [2]. ShuYan Liu, et al. A small molecule induces integrin β4 nuclear translocation and apoptosis selectively in cancer cells with high expression of integrin β4. Oncotarget. 2016 Mar 29; 7(13): 16282–16296. [Content Brief]
Keywords
