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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
26 Results for "
AO
" in MedChemExpress (MCE) Product Catalog:
Products (26)
26 Results for "AO" in MCE Product Catalog:
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1 Cited Publications
Synonyms: Galangin 3-methyl ether; 3-Methylgalangin
Category:
Infection Flavonols Flavonoids Phenols Polyphenols Alpinia officinarum Hance Plants Disease Research Fields Zingiberaceae
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Alcohol oxidase is a functional enzyme of methanol utilization pathway and can be isolated from yeast peroxisome .
Cat. No.: HY-136779
CAS No.: 36443-68-2
Synonyms: AO-245
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Antioxidant 245 (AO-245) is a hindered phenol antioxidant. Antioxidant 245 can be used in the research of nanocomposites .
Cat. No.: HY-P3586
CAS No.: 859216-15-2
Synonyms: Hunter-killer peptide AO; Prohibitin-targeting peptide 1; prohibitin-TP01; Adipotide
Cat. No.: HY-179177
CAS No.: 1081122-55-5
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AO-365/43472821 is a selective, brain-penetrant Dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A) inhibitor (IC50 = 0.29 μM) and shows a significant inhibitory effect on (CDC-like kinase 1) CLK1 (IC50 = 0.08 μM). AO-365/43472821 could protect the human neuroblastoma cell line SH-SY5Y from Okadaic acid (HY-N6785) (OA)-induced injury. AO-365/43472821 decreased tau (pSer396)/tau and Aβ1-42 protein expression. AO-365/43472821 can be used for the study of Alzheimer's disease .
Cat. No.: HY-159130
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AO-022 is a potent TALDO1 allosteric inhibitor. AO-022 decreases the expression of vimentin and snail. AO-022 shows antiproliferative activity and antitumor activity. AO-022 has the potential for the research of breast cancer .
Synonyms: AO-33; (±)-Losigamone; LSG
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Losigamone (AO-33) is an orally active antiepileptic compound. Losigamone blocks sodium channel. Losigamone stimulates the neuronal chloride channel and enhance chloride influx. Losigamone potentiates GABA-mediated responses and reduces epileptiform activity induced by chloride channel antagonists. Losigamone can be used for epilepsy research .
Cat. No.: HY-P991561
CAS No.: 2691109-74-5
Cat. No.: HY-165362
CAS No.: 87178-48-1
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AO-1535 is a semisynthetic monoglycosylceramide that inhibits the production of reactive oxygen intermediates in human monocytes and macrophages stimulated by phorbol ester and chemotactic tetrapeptide. AO-1535 can be used for the research of inflammatory dermatoses .
Cat. No.: HY-N8285
CAS No.: 88418-12-6
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Cat. No.: HY-RI01651A
hsa-miR-548ao-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
Cat. No.: HY-144075
CAS No.: 3035893-19-4
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JAK-IN-19 is a potent JAK inhibitor (PBMC IFNγ pIC50=7.2 and HLF Eotaxin pIC50=7.7). JAK-IN-19 has good retentive properties in the lung via mitigating being metabolized by Aldehyde Oxidase (AO), with diminished VEGFR2 selectivity (VEGFR2 pIC50=7.0, Aurora B pIC50=5.8) .
Cat. No.: HY-RS00775
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AOX1 Human Pre-designed siRNA Set A contains three designed siRNAs for AOX1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS17631
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Aox1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Aox1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-136779S
Synonyms: AO-245-d12
Cat. No.: HY-RI01650
hsa-miR-548ao-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
