1 Result for "

AZ12601011

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "AZ12601011" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-122856
CAS No.: 2748337-86-0
Purity:  99.88%
Target:  

TGF-β Receptor

Research Areas:  

Cancer

AZ12601011 is an orally active, selective TGFBR1 kinase inhibitor with an IC50 of 18 nM and a Kd of 2.9 nM. AZ12601011 inhibits phosphorylation of SMAD2 via selectively inhibiting ALK4, TGFBR1, and ALK7. AZ12601011 inhibits mammary tumor growth .
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