2 Results for "

Ac-LPSDDLEFWCHVMY-NH2

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Ac-LPSDDLEFWCHVMY-NH2" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-P1454
CAS No.: 2247635-23-8
Synonyms: Ac-LPSDDLEFWCHVMY-NH2
Target:  

Wnt

Research Areas:  

Cancer

Fz7-21 (Ac-LPSDDLEFWCHVMY-NH2) is a potent peptide antagonist of FZD7 receptors , selectively binds to FZD7 CRD subclass and alters the conformation of the CRD and the architecture of its lipid-binding groove. The EC50 values are 58 and 34 nM for human and mouse FZD7 CRD, respectively. Fz7-21 impairs the function of FZD7 in Wnt–β-catenin signalling and stem cell function in intestinal organoids [2].
loading...
    loading...
3
3 Cited Publications
Cat. No.: HY-P1454A
Synonyms: Ac-LPSDDLEFWCHVMY-NH2 TFA
Target:  

Wnt

Research Areas:  

Cancer

Fz7-21 (Ac-LPSDDLEFWCHVMY-NH2) TFA is a potent peptide antagonist of FZD7 receptors , selectively binds to FZD7 CRD subclass and alters the conformation of the CRD and the architecture of its lipid-binding groove. The EC50 values are 58 and 34 nM for human and mouse FZD7 CRD, respectively. Fz7-21 TFA impairs the function of FZD7 in Wnt-β-catenin signalling and stem cell function in intestinal organoids [2].
loading...
    loading...