4 Results for "

Adomeglivant

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "Adomeglivant" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-19904
CAS No.: 1488363-78-5
Synonyms: LY2409021
Target:  

GCGR

Research Areas:  

Metabolic Disease

Adomeglivant (LY2409021) is a potent, selective glucagon receptor (GluR) allosteric antagonist. Adomeglivant is widely used in the research for type 2 diabetes mellitus .
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Cat. No.: HY-19904A
CAS No.: 872260-47-4
Synonyms: (+/-)-LY2409021
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

(+/-)-Adomeglivant ((+/-)-LY2409021) is a potent and selective glucagon receptor antagonist with hypoglycemic activity. (+/-)-Adomeglivant is effective in lowering blood sugar levels in both healthy people and people with type 2 diabetes. (+/-)-Adomeglivant is well tolerated by glucagon signaling blockade in patients with type 2 diabetes and significantly reduces fasting and postprandial blood glucose with a concomitant reversible elevation of aminotransferases. Glucagon signaling inhibition by (+/-)-Adomeglivant is a promising potential inhibitory approach for patients with type 2 diabetes and warrants further evaluation of its benefits and risks in longer clinical trials .
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Cat. No.: HY-19904B
CAS No.: 872260-19-0
Synonyms: (+)-LY2409021
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

(+)-Adomeglivant ((+)-LY2409021) is a potent and selective glycogenotropin receptor antagonist with glucose-lowering activity. (+)-Adomeglivant reduces fasting blood glucose levels in both healthy subjects and patients with type 2 diabetes. The use of (+)-Adomeglivant can help investigate the mechanisms of hyperglycemia in type 2 diabetes. The antagonistic effect of (+)-Adomeglivant makes it challenging to assess the metabolic consequences of postprandial hyperglycemia .
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Cat. No.: HY-19904R
CAS No.: 1488363-78-5
Synonyms: LY2409021 (Standard)
Research Areas:  

Metabolic Disease

Adomeglivant (Standard) is the analytical standard of Adomeglivant. This product is intended for research and analytical applications. Adomeglivant (LY2409021) is a potent, selective glucagon receptor (GluR) allosteric antagonist. Adomeglivant is widely used in the research for type 2 diabetes mellitus .
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