(+/-)-Adomeglivant
(+/-)-Adomeglivant ((+/-)-LY2409021) is a potent and selective glucagon receptor antagonist with hypoglycemic activity. (+/-)-Adomeglivant is effective in lowering blood sugar levels in both healthy people and people with type 2 diabetes. (+/-)-Adomeglivant is well tolerated by glucagon signaling blockade in patients with type 2 diabetes and significantly reduces fasting and postprandial blood glucose with a concomitant reversible elevation of aminotransferases. Glucagon signaling inhibition by (+/-)-Adomeglivant is a promising potential inhibitory approach for patients with type 2 diabetes and warrants further evaluation of its benefits and risks in longer clinical trials.
For research use only. We do not sell to patients.
- CAS No.: 872260-47-4
- Formula: C32H36F3NO4
- Molecular Weight:555.63
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
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Biological Activity
Chemical Information
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CAS No. 872260-47-4
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Molecular Weight 555.63
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Formula C32H36F3NO4
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SMILES
O=C(CCNC(C1=CC=C(C(CCC(F)(F)F)OC2=CC(C)=C(C3=CC=C(C(C)(C)C)C=C3)C(C)=C2)C=C1)=O)O
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Synonyms
(+/-)-LY2409021
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
(+/-)-Adomeglivant Related Classifications
HY-19904A Related Classifications
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