1 Result for "

And1-IN-1

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "And1-IN-1" in MCE Product Catalog:

Cat. No.: HY-150184
CAS No.: 2451028-69-4
Purity:  98.01%
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

And1-IN-1 is a potent And1 inhibitor with an IC50 of 2.08 μM. And1-IN-1 binds to the N-terminus of And-1 and induces a conformational change in And-1, which promotes the interaction of And-1 with E3 ligase CUL4B for ubiquitin-mediated degradation. And1-IN-1 suppresses the growth of a broad range of cancers and resensitizes platinum-resistant ovarian cancer cells to platinum agents. And1-IN-1 can be used for the studies of ovarian cancer and breast cancer .
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