4 Results for "

Autophagy-IN-8

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "Autophagy-IN-8" in MCE Product Catalog:

Cat. No.: HY-183803
CAS No.: 2027550-79-2
Target:  

Autophagy

Research Areas:  

Cancer

Autophagy-IN-8 is an autophagy inhibitor. Autophagy-IN-8 exhibits antiproliferative activity against cancer cells. Autophagy-IN-8 can be used in the research of melanoma and pancreatic cancer .
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5
5 Cited Publications
Cat. No.: HY-N0447
CAS No.: 23513-08-8
8-Gingerol can be found in the rhizome of ginger (Z. officinale) and has oral bioactivity. It activates TRPV1, with an EC50 value of 5.0 µM. 8-Gingerol inhibits COX-2 and also suppresses the growth of H. pylori in vitro. Additionally, 8-Gingerol exhibits anticancer, antioxidant, and anti-inflammatory properties by inhibiting the epidermal growth factor receptor (EGFR) and modulating its downstream STAT3/ERK pathway to suppress the proliferation, migration, and invasion of colorectal cancer cells. 8-Gingerol also exerts immunosuppressive effects by inhibiting oxidative stress, inducing cell cycle arrest, promoting apoptosis, and regulating autophagy. Furthermore, 8-Gingerol has cardioprotective effects. 8-Gingerol is promising for research in the fields of cancer, infection, immunosuppression, and cardiovascular diseases.
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Cat. No.: HY-183803A
CAS No.: 2027550-81-6
Target:  

Autophagy

Research Areas:  

Cancer

Autophagy-IN-8 (DQ 660) hydrochloride is an autophagy inhibitor with antiproliferative activity against cancer cells. Autophagy-IN-8 hydrochloride exhibits antiproliferative activity against melanoma and pancreatic cancer cells. Autophagy-IN-8 hydrochloride can be used in the research of melanoma and pancreatic cancer .
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Cat. No.: HY-134314
CAS No.: 913645-39-3
8-Nitro-cGMP is an electrophilic second messenger of redox signaling that can form a protein-S-cGMP adduct in s-guanylation process. 8-Nitro-cGMP is an autophagy inducer. 8-Nitro-cGMP promotes RANKL-induced osteoclast differentiation from macrophages. 8-Nitro-cGMP has vasodilator effect, and ameliorates the vascular endothelial dysfunction in diabetic mice .
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