2 Results for "

BCL6-IN-10

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "BCL6-IN-10" in MCE Product Catalog:

Cat. No.: HY-177755
CAS No.: 2230406-52-5
Target:  

Molecular Glues BCL6

Research Areas:  

Cancer

BCL6-IN-10 (Compound 6) is a selective partially degradable molecular glue inhibitor that targets the BTB domain of BCL6 with an IC50 of 4 nM. BCL6-IN-10 shows anti-proliferative effect in diffuse large B-cell lymphoma (DLBCL) cell lines. BCL6-IN-10 can be used for the research of cancer .
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Cat. No.: HY-149522
CAS No.: 3034883-70-7
Target:  

Bcl-2 Family Apoptosis

Research Areas:  

Cancer

BCL6-IN-10 (Compound WK499) is a BCL6 inhibitor. BCL6-IN-10 interrupts the binding of BCL6 to SMRT protein. BCL6-IN-10 induces cell apoptosis, cell cycle arrest and DNA damage. BCL6-IN-10 inhibits AML cell proliferation (IC50s: 0.91, 1.63, 1.026, 7.42, 0.87, 0.85μM for OCl-AML3, THP1, MOLM13, HL60, KG1, NB4 cell respectively) .
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