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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
17 Results for "
Bazedoxifene
" in MedChemExpress (MCE) Product Catalog:
Products (17)
17 Results for "Bazedoxifene" in MCE Product Catalog:
17
Target:
Research Areas:
Bazedoxifene (TSE-424) is an oral, BBB-penetrant nonsteroidal selective estrogen receptor modulator (SERM), with IC50s of 23 nM and 99 nM for ERα and ERβ, respectively. Bazedoxifene can be used for the research of osteoporosis. Bazedoxifene also acts as an inhibitor of IL-6/GP130 protein-protein interactions and can be used for the research of pancreatic cancer .
17
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Research Areas:
Bazedoxifene acetate (TSE-424 acetate) is an oral, nonsteroidal selective estrogen receptor modulator (SERM), with IC50s of 23 nM and 99 nM for ERα and ERβ, respectively. Bazedoxifene acetate can be used for the research of osteoporosis. Bazedoxifene acetate also acts as an inhibitor of IL-6/GP130 protein-protein interactions and can be used for the research of pancreatic cancer .
Cat. No.: HY-A0036D
CAS No.: 198481-33-3
Synonyms: TSE-424 acetate-D
Target:
Research Areas:
Bazedoxifene (acetate)-D (TSE-424 (acetate)-D) is the D-crystal form compound of Bazedoxifene acetate (HY-A0036). Bazedoxifene acetate is an orally active, nonsteroidal selective estrogen receptor modulator (SERM), with IC50s of 23 nM and 99 nM for ERα and ERβ, respectively .
Cat. No.: HY-A0036B
CAS No.: 198481-33-3
Synonyms: TSE-424 acetate-B
Target:
Research Areas:
Bazedoxifene (acetate)-B (TSE-424 (acetate)-B) is the B-crystal form compound of Bazedoxifene acetate (HY-A0036).
Cat. No.: HY-A0031A
CAS No.: 198480-56-7
Synonyms: TSE-424 hydrochloride
Target:
Research Areas:
Bazedoxifene hydrochloride (TSE-424 hydrochloride) is an oral active, BBB-penetrant nonsteroidal selective estrogen receptor modulator (SERM), with IC50s of 23 nM and 99 nM for ERα and ERβ, respectively. Bazedoxifene hydrochloride can be used for the research of osteoporosis. Bazedoxifene hydrochloride acts as an inhibitor of IL-6/GP130 protein-protein interactions. Bazedoxifene hydrochloride can be used for the research of pancreatic cancer .
Cat. No.: HY-A0036R
CAS No.: 198481-33-3
Synonyms: TSE-424 acetate (Standard)
Research Areas:
Bazedoxifene (acetate) (Standard) is the analytical standard of Bazedoxifene (acetate). This product is intended for research and analytical applications. Bazedoxifene acetate (TSE-424 acetate) is an oral, nonsteroidal selective estrogen receptor modulator (SERM), with IC50s of 23 nM and 99 nM for ERα and ERβ, respectively. Bazedoxifene acetate can be used for the research of osteoporosis. Bazedoxifene acetate also acts as an inhibitor of IL-6/GP130 protein-protein interactions and can be used for the research of pancreatic cancer .
Cat. No.: HY-143929S
Cat. No.: HY-A0031S2
CAS No.: 1795027-71-2
Synonyms: TSE-424-d4 acetate
Cat. No.: HY-A0031R
CAS No.: 198481-32-2
Synonyms: TSE-424 (Standard)
Research Areas:
Bazedoxifene (Standard) is the analytical standard of Bazedoxifene. This product is intended for research and analytical applications. Bazedoxifene (TSE-424) is an oral, BBB-penetrant nonsteroidal selective estrogen receptor modulator (SERM), with IC50s of 23 nM and 99 nM for ERα and ERβ, respectively. Bazedoxifene can be used for the research of osteoporosis. Bazedoxifene also acts as an inhibitor of IL-6/GP130 protein-protein interactions and can be used for the research of pancreatic cancer .
Cat. No.: HY-A0031S
CAS No.: 1133695-49-4
Synonyms: TSE-424-d4
Cat. No.: HY-Z0833
CAS No.: 1174289-22-5
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Research Areas:
Bazedoxifene N-Oxide is the oxidative degradation product of selective estrogen receptor modulator (SERM) Bazedoxifene .
Cat. No.: HY-131194
CAS No.: 2485758-50-5
Target:
Research Areas:
JAK2/STAT3-IN-1 (compound (S)-10a) is a potent GP130 inhibitor with an IC50 of 3.04 µM. JAK2/STAT3-IN-1 shows anti-tumor activity .
Cat. No.: HY-168072
CAS No.: 2955243-69-1
Target:
Research Areas:
GP130-IN-1 (compound 49) is a potent GP130 inhibitor with significant in vitro antitumor activity and higher selectivity than Bazedoxifene (HY-A0031). GP130-IN-1 induces ultrastructural changes in cells, causing cell cycle arrest in the G0/G1 phase in a time-dependent manner and triggering apoptosis and autophagy. GP130-IN-1 can be used in the study of triple-negative breast cancer .
Cat. No.: HY-Z1046
CAS No.: 479075-72-4
Target:
Research Areas:
Bazedoxifene impurity 2 is an impurity of Bazedoxifene (HY-A0031).
Cat. No.: HY-167818
CAS No.: 328933-67-1
Cat. No.: HY-Z1046R
CAS No.: 479075-72-4
Target:
N-(4-(Benzyloxy)phenyl)formamide (Standard) is the analytical standard of N-(4-(Benzyloxy)phenyl)formamide. This product is intended for research and analytical applications.
Cat. No.: HY-180791
SARS-CoV-2-IN-121 (Compound 74) is a SARS-CoV-2 virus inhibitor. SARS-CoV-2-IN-121 exhibits IC50 values in the pseudovirus and live virus systems of 1.6 and 0.45 μM respectively. SARS-CoV-2-IN-121 effectively inhibits the replication or protein expression of the virus within cells and has almost no toxicity to host cells. SARS-CoV-2-IN-121 can be used for SARS-CoV-2 virus infection research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
