JAK2/STAT3-IN-1
JAK2/STAT3-IN-1 (compound (S)-10a) is a potent GP130 inhibitor with an IC50 of 3.04 µM. JAK2/STAT3-IN-1 shows anti-tumor activity.
For research use only. We do not sell to patients.
- CAS No.: 2485758-50-5
- Formula: C34H35BrF3N5O2
- Molecular Weight:682.57
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
IC50: 3.04 µM (GP130)[1]
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
3.04 μM
Compound: (S)-10a
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Antiproliferative activity against human A549 cells assessed as cell growth inhibition measured after 24 hrs by MTT assay
Antiproliferative activity against human A549 cells assessed as cell growth inhibition measured after 24 hrs by MTT assay
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[PMID: 32388278] |
Chemical Information
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CAS No. 2485758-50-5
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Molecular Weight 682.57
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Formula C34H35BrF3N5O2
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SMILES
O=C(N1N=C(C2=CC=C(C(F)(F)F)C=C2)C[C@H]1C3=CN(CC4=CC=C(OCCN5CCCCCC5)C=C4)C6=C3C=C(Br)C=C6)N
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
JAK2/STAT3-IN-1 Related Classifications
HY-131194 Related Classifications
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