5 Results for "

C19-steroids

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "C19-steroids" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-135794
CAS No.: 32694-37-4
Purity:  ≥98.0%
Synonyms: 11-KDHT; 5α-Dihydro-11-keto testosterone
Target:  

Androgen Receptor

Research Areas:  

Endocrinology

11-Ketodihydrotestosterone (11-KDHT; 5α-Dihydro-11-keto testosterone) is an endogenous steroid and a metabolite of 11β-Hydroxyandrostenedione. 11-Ketodihydrotestosterone is an active androgen and is also a potent androgen receptor (AR) agonist with a Ki of 20.4 nM and an EC50 of 1.35 nM for human AR. 11-Ketodihydrotestosterone drives gene regulation, protein expression and cell growth in androgen-dependent prostate cancer cells .
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Cat. No.: HY-113302
CAS No.: 510-64-5
Purity:  99.11%
19-Hydroxyandrost-4-ene-3,17-dione is an endogenous adrenal C19 steroid and also an agonist of the olfactory receptor OR51E2, with an EC50 of 0.15 nM. 19-Hydroxyandrost-4-ene-3,17-dione activates G protein-coupled receptor signaling pathways, drives neuroendocrine transdifferentiation, induces G0/G1 cell cycle arrest, reduces apoptosis and anabolic signaling, decreases cell viability, and reprograms cell metabolic profiles. 19-Hydroxyandrost-4-ene-3,17-dione induces sodium retention and hypertension, and its secretion is regulated by ACTH and the renin-angiotensin system. 19-Hydroxyandrost-4-ene-3,17-dione can be used in research related to prostate cancer, metastatic breast cancer, and hypertension .
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Cat. No.: HY-135794R
CAS No.: 32694-37-4
Synonyms: 11-KDHT (Standard); 5α-Dihydro-11-keto testosterone (Standard)
Research Areas:  

Endocrinology

11-Ketodihydrotestosterone (Standard) is the analytical standard of 11-Ketodihydrotestosterone. This product is intended for research and analytical applications. 11-Ketodihydrotestosterone (11-KDHT; 5α-Dihydro-11-keto testosterone) is an endogenous steroid and a metabolite of 11β-Hydroxyandrostenedione. 11-Ketodihydrotestosterone is an active androgen and is also a potent androgen receptor (AR) agonist with a Ki of 20.4 nM and an EC50 of 1.35 nM for human AR. 11-Ketodihydrotestosterone drives gene regulation, protein expression and cell growth in androgen-dependent prostate cancer cells .
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Cat. No.: HY-N17596
CAS No.: 7801-30-1
Synonyms: 11OHDHT; 5a-Dihydro-11β-hydroxytestosterone
Target:  

Others

11β,17β-Dihydroxy-5α-androstan-3-one (11OHDHT) is a C11-oxy C19 steroid, has a role as an androgen. 11β,17β-Dihydroxy-5α-androstan-3-one can be used for prostate cancer research .
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Cat. No.: HY-E72116
Target:  

UGT

Human UGT2B4 is a UDP-glucuronosyltransferase. UGT2B4 catalyzes the glucuronidation of bile acids, Carvedilol (HY-B0006) and 6-hydroxylated bile acids to form glucuronide derivatives. UGT2B4 participates in the inactivation of endogenous and exogenous substances, including catechol estrogens, C19 steroids, phenols and monoterpenoids. Human UGT2B4 can be used in the research of hypertension, angina pectoris, chronic heart failure and intrahepatic cholestasis .
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