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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
24 Results for "
C2-amide
" in MedChemExpress (MCE) Product Catalog:
Products (24)
24 Results for "C2-amide" in MCE Product Catalog:
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1 Cited Publications
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(S,R,S)-AHPC-C2-amide-benzofuranylmethyl-pyridine is a dual-targeting PROTAC molecule. (S,R,S)-AHPC-C2-amide-benzofuranylmethyl-pyridine not only targets the ubiquitination and degradation of Smad3, but also elevates the protein level of HIF-α, thereby exerting multi-pathway anti-fibrotic and renoprotective effects. (S,R,S)-AHPC-C2-amide-benzofuranylmethyl-pyridine can be used in a wide range of tumor studies including cancers with KRAS inhibitor resistance, covering pancreatic ductal adenocarcinoma, acute myeloid leukemia, and various soft tissue sarcomas (such as fibrosarcoma, liposarcoma, chondrosarcoma, etc.). (S,R,S)-AHPC-C2-amide-benzofuranylmethyl-pyridine can also be applied to research related to various solid tumors and hematological malignancies, involving multiple cancer types such as colon cancer, breast cancer, ovarian cancer, non-small cell lung cancer, glioblastoma, and melanoma .
Cat. No.: HY-P4070
CAS No.: 1188379-43-2
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Indole-C2-amide-C2-NH2 is a potent linker .
Cat. No.: HY-171814
CAS No.: 3032302-82-9
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Mal-PEG2-amide-C2-amide-Phenyl (β-D-glucuronide)-NMT-IN-7 is an drug-linker conjugate for ADC that contains a potent NMT inhibitor (NMT-IN-7), with an IC50 of 2.1 nM against HsNMT1. Mal-PEG2-amide-C2-amide-Phenyl (β-D-glucuronide)-NMT-IN-7 consists of an NMT inhibitor (HY-160945) and a stable cleavable linker (Mal-PEG2-amide-C2-amide-Phenyl (β-D-glucuronide)). Mal-PEG2-amide-C2-amide-Phenyl (β-D-glucuronide)-NMT-IN-7 can be used for ADC synthesis and breast cancer-related research .\n
Cat. No.: HY-403978S
CAS No.: 1447799-45-2
Cat. No.: HY-145245
Purity: 99.62%
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TLR4-IN-C34-C2-amide-C6-OH is a linker that incorporates TLR4 inhibitor TLR4-IN-C34. TLR4-IN-C34 inhibits TLR4 in enterocytes and macrophages, and reduces systemic inflammation in mouse models of endotoxemia and necrotizing enterocolitis .
Cat. No.: HY-145253
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Tri(TLR4-IN-C34-C2-amide-PEG1)-amide-C3-COOH is a linker that incorporates TLR4 inhibitor TLR4-IN-C34. TLR4-IN-C34 inhibits TLR4 in enterocytes and macrophages, and reduces systemic inflammation in mouse models of endotoxemia and necrotizing enterocolitis .
Cat. No.: HY-145255
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Tri(TLR4-IN-C34-C2-amide-C3-amide-PEG1)-amide-C3-COOH is a linker that incorporates TLR4 inhibitor TLR4-IN-C34. TLR4-IN-C34 inhibits TLR4 in enterocytes and macrophages, and reduces systemic inflammation in mouse models of endotoxemia and necrotizing enterocolitis .
Cat. No.: HY-P11293
CAS No.: 1309855-53-5
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Cat. No.: HY-P4757
CAS No.: 108081-77-2
Cat. No.: HY-P1321
CAS No.: 158859-98-4
Synonyms: 1229U91; GW1229
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Cat. No.: HY-160235
CAS No.: 2732859-29-7
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Pomalidomide-C2-amide-C5-azidea is an E3 linker conjugate, pomalidomide, that can be used to synthesize highly effective PROTAC molecules towards CDK9. Pomalidomide-C2-amide-C5-azidea has antiproliferative activity .
Cat. No.: HY-164391
CAS No.: 2545963-02-6
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Pomalidomide-C2-amide-C4-Br is an E3 ligase ligand-linker conjugate containing a Pomalidomide (HY-10984) based cereblon (CRBN) ligand and a linker. Pomalidomide-C2-amide-C4-Br can be used in the synthesis of PROTACs .
Cat. No.: HY-148472A
CAS No.: 99789-97-6
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C2-Amide-C4-NH2 is a potent linker .
Cat. No.: HY-139085A
Purity: ≥95.0%
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XL388-C2-amide-PEG9-NH2 hydrochloride is an intermediate used in the synthesis of C26-linked Rapamycin analog .
Cat. No.: HY-139085B
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XL388-C2-amide-PEG9-NH2 TFA is an intermediate used in the synthesis of C26-linked Rapamycin analog .
Cat. No.: HY-P1321A
Synonyms: 1229U91 TFA; GW1229 TFA
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Cat. No.: HY-171342
CAS No.: 2893765-20-1
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Mal-C2-amide-C10-tri-GalNAc is an asialoglycoprotein receptor (ASGPR) binding ligand fragment and a component of lysosome-targeted bifunctional molecules. Mal-C2-amide-C10-tri-GalNAc is used in the research of autoimmune diseases .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
