Tri(TLR4-IN-C34-C2-amide-PEG1)-amide-C3-COOH
Tri(TLR4-IN-C34-C2-amide-PEG1)-amide-C3-COOH is a linker that incorporates TLR4 inhibitor TLR4-IN-C34. TLR4-IN-C34 inhibits TLR4 in enterocytes and macrophages, and reduces systemic inflammation in mouse models of endotoxemia and necrotizing enterocolitis.
For research use only. We do not sell to patients.
- Formula: C78H125N7O36
- Molecular Weight:1736.85
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All PROTAC Linkers Isoforms
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Biological Activity
Description
IC50 & Target
[1]|
Alkyl/ether |
TLR4 |
Chemical Information
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Molecular Weight 1736.85
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Formula C78H125N7O36
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SMILES
O=C(NCCCCCCOC1O[C@@H](COC(C)=O)[C@@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1NC(C)=O)CCOCC(COCCC(NCCCCCCOC2O[C@H](COC(C)=O)[C@H](OC(C)=O)[C@H](OC(C)=O)[C@H]2NC(C)=O)=O)(COCCC(NCCCCCCOC3O[C@@H](COC(C)=O)[C@@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]3NC(C)=O)=O)NC(CCCC(O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)