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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
75 Results for "
C21
" in MedChemExpress (MCE) Product Catalog:
Products (75)
75 Results for "C21" in MCE Product Catalog:
6
6 Publications Verification
Synonyms: AT2 receptor agonist C21
Research Areas:
Cardiovascular Disease Neurological Disease Inflammation/Immunology
Buloxibutid (AT2 receptor agonist C21) is an orally active, selective angiotensin II type 2 receptor (AT2R) agonist, with a Ki value of 0.4 nM for porcine AT2R. Buloxibutid exerts effects such as vasodilation, anti-inflammation, anti-fibrosis (promoting the expression of collagenase MMP-13) and tissue repair mainly by activating the NO/cGMP pathway, inhibiting the pro-proliferative MAPK signaling, and suppressing the pro-fibrotic TGF-β/Smad pathway as well as the inflammatory NF-κB pathway. Buloxibutid can be used in research related to idiopathic pulmonary fibrosis, hypertension, and systemic sclerosis .
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1
1 Cited Publications
Cat. No.: HY-N1983
CAS No.: 38395-02-7
Cat. No.: HY-N2103
CAS No.: 191729-43-8
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Cat. No.: HY-N1375
CAS No.: 84745-94-8
Category:
Monophenols Asclepiadaceae Phenols Cynanchum otophyllum Schneid． Plants Disease Research Fields Cancer Steroids
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Cat. No.: HY-N2102
CAS No.: 191729-44-9
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Cat. No.: HY-N1983R
CAS No.: 38395-02-7
Category:
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Cat. No.: HY-124486
CAS No.: 21170-34-3
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Research Areas:
NSC-88915 is an inhibitor of Tdp1 with an IC50 of 7.7 μM. NSC-88915 is a C21-subsitited progesterone derivative .
Cat. No.: HY-N0582
CAS No.: 106758-54-7
Category:
Neurological Disease Anti-aging Asclepiadaceae Cynanchum otophyllum Schneid． Plants Disease Research Fields Steroids
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Cat. No.: HY-132271
CAS No.: 23214-93-9
Category:
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Cat. No.: HY-100113A
CAS No.: 1947313-60-1
Synonyms: AT2 receptor agonist C21 hydrochloride
Research Areas:
Cardiovascular Disease Neurological Disease Inflammation/Immunology
Buloxibutid (AT2 receptor agonist C21) hydrochloride is an orally active, selective angiotensin II type 2 receptor (AT2R) agonist, with a Ki value of 0.4 nM for porcine AT2R. Buloxibutid hydrochloride exerts vasodilatory, anti-inflammatory, antifibrotic (promoting the expression of collagenase MMP-13) and tissue repair effects mainly by activating the NO/cGMP pathway, inhibiting the pro-proliferative MAPK signaling, and suppressing the pro-fibrotic TGF-β/Smad pathway and inflammatory NF-κB pathway. Buloxibutid hydrochloride can be used in research related to idiopathic pulmonary fibrosis, hypertension, systemic sclerosis and other conditions .
Cat. No.: HY-100113R
CAS No.: 477775-14-7
Synonyms: AT2 receptor agonist C21 (Standard)
Research Areas:
Cardiovascular Disease Neurological Disease Inflammation/Immunology
Buloxibutid (AT2 receptor agonist C21) (Standard) is the analytical standard of Buloxibutid (HY-100113). This product is intended for research and analytical applications. Buloxibutid is an orally active, selective angiotensin II type 2 receptor (AT2R) agonist, with a Ki value of 0.4 nM for porcine AT2R. Buloxibutid exerts effects such as vasodilation, anti-inflammation, anti-fibrosis (promoting the expression of collagenase MMP-13) and tissue repair mainly by activating the NO/cGMP pathway, inhibiting the pro-proliferative MAPK signaling, and suppressing the pro-fibrotic TGF-β/Smad pathway as well as the inflammatory NF-κB pathway. Buloxibutid can be used in research related to idiopathic pulmonary fibrosis, hypertension, and systemic sclerosis.
Cat. No.: HY-N0581
CAS No.: 106644-33-1
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Cat. No.: HY-N12720
CAS No.: 1800029-53-1
Category:
Apocynaceae Cardiacglycosides Plants Vincetoxicum atratum (Bunge) Morren et Decne. Steroids
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Cat. No.: HY-W779002
CAS No.: 261728-61-4
Cat. No.: HY-Y0383S2
CAS No.: 432028-02-9
Cat. No.: HY-RS01739
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C21orf58 Human Pre-designed siRNA Set A contains three designed siRNAs for C21orf58 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
