1 Result for "

CCKBR agonist2

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "CCKBR agonist2" in MCE Product Catalog:

Cat. No.: HY-179721
CAS No.: 923714-61-8
Research Areas:  

Neurological Disease

CCKBR agonist-2 (Compound z-44) is a Gi-preferring CCKBR agonist. CCKBR agonist-2 effectively activates the CCKBR-Gi signaling pathway (EC50 = 0.27 nM), but has almost no activity on Gq and Gs signaling pathways. CCKBR agonist-2 shows no significant protective effect in the mouse Alzheimer's disease model, proving that the simple activation of the Gi signal pathway does not play a dominant role in the improvement of cognitive function .
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