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Contact toxicity

" in MedChemExpress (MCE) Product Catalog:

12

Inhibitors & Agonists

4

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B1946
    Dimethoate
    5 Publications Verification

    		 Environmental Pollutants Apoptosis Cholinesterase (ChE) Insecticide Reactive Oxygen Species (ROS) Inflammation/Immunology
    Dimethoate is an organophosphate insecticide and acaricide. Dimethoate is an orally active acetylcholinesterase inhibitor. Dimethoate induces reactive oxygen species (ROS). Dimethoate induces DNA damage and cell apoptosis in vivo. Dimethoate affect immune system in mice .
    Dimethoate
  • HY-127032
    Polyquaternium-1

    Polidronium chloride

    		 Biochemical Assay Reagents Infection
    Polyquaternium-1 (Polidronium chloride; PQ-1) is an antimicrobial preservative and an activator of NF-κB. Polyquaternium-1 targets bacterial cell membranes, commonly used in ophthalmic surgery. Polyquaternium-1 adsorbs to the surface of microbial membranes through its polycationic properties, destroying membrane integrity and inducing potassium ion leakage, leading to bacterial death. Polyquaternium-1 exerts antimicrobial effects at a concentration of 0.001% and has low toxicity to mammalian cells. Polyquaternium-1 can be used to prepare products such as glaucoma eye drops (Travoprost preparations containing PQ-1), artificial tears, and contact lens solutions to reduce the ocular surface toxicity of traditional preservatives such as benzalkonium chloride (HY-B2232) .
    Polyquaternium-1
  • HY-W015616
    Benzylacetone

    4-Penylbutan-2-one

    		 Environmental Pollutants Tyrosinase Infection Metabolic Disease
    Benzylacetone (4-Penylbutan-2-one) is an aromatic compound. Benzylacetone is a mushroom tyrosinase inhibitor with an IC50 of 2.8 mM, a Ki of 1.25 mM for monophenolase and an IC50 of 0.6 mM, a Ki of 0.39 mM for diphenolase. Benzylacetone inhibits free mushroom tyrosinase and enzyme-substrate complex. Benzylacetone acts as an appetite enhancer via olfactory stimulation, reduces spontaneous locomotor activity, induces weight gain. Benzylacetone exhibits repellent, fumigant, and contact toxicity against Tribolium castaneum adults .
    Benzylacetone
  • HY-138149
    2-epi-Abamectin

    epi-Avermectin B1a

    		 Drug Metabolite Infection
    2-epi-Abamectin is a degradation product of Abamectin. It is toxic to the two-spotted spider mite in a contact assay with an LC50 value of 4 ppm, which is approximately 100-fold less potent than abamectin.
    2-epi-Abamectin
  • HY-B1946R
    Dimethoate (Standard)

    		Insecticide Reference Standards Reactive Oxygen Species (ROS) Apoptosis Cholinesterase (ChE) Inflammation/Immunology
    Dimethoate (Standard) is the analytical standard of Dimethoate. This product is intended for research and analytical applications. Dimethoate is an organophosphate insecticide and acaricide. Dimethoate is an orally active acetylcholinesterase inhibitor. Dimethoate induces reactive oxygen species (ROS). Dimethoate induces DNA damage and cell apoptosis in vivo. Dimethoate affect immune system in mice.
    Dimethoate (Standard)
  • HY-133848
    Alanycarb

    OK-135

    		 Insecticide Infection
    Alanycarb (OK-135) is a broad-spectrum oxime carbamate insecticide with contact and oral toxicity. Alanycarb is effective against a wide variety of insect pests and is a pro-insecticide. The principal active molecule produced by the biological modification of Alanycarb within target organisms is methomyl .
    Alanycarb
  • HY-N10100
    Epiglobulol

    		Others Others
    Epiglobulol is a natural product that can be isolated from Atalantia buxifolia. Epiglobulol is a principal components of essential oil which has significant contact toxicity against three stored-product insects .
    Epiglobulol
  • HY-W335896
    4-(2-Octylamino)diphenylamine

    		Bacterial Infection Inflammation/Immunology
    4-(2-Octylamino)diphenylamine is an aromatic amine antioxidant, which is toxic to V. fischeri with an IC50 value of 0.68 mg/mL. 4-(2-Octylamino)diphenylamine induces skin sensitization and contact dermatitis in a local lymph node assay in mice. 4-(2-Octylamino)diphenylamine can be used as an additive in rubber .
    4-(2-Octylamino)diphenylamine
  • HY-W269352
    2-Dodecanone

    		Insecticide Infection
    2-Dodecanone is an insecticide with repellent activity against specific insect species. 2-Dodecanone exhibits contact toxicity against adult Tribolium castaneum, Lasioderma serricorne and Liposcelis bostrychophila. 2-Dodecanone shows repellent effects against adult Lasioderma serricorne .
    2-Dodecanone
  • HY-N3076
    Phyllostine

    (-)-Phyllostine; Phyllostin

    		 Others Others
    Phyllostine ((-)-Phyllostine) can be isolated from D. miriciae. Phyllostine exhibits strong antifeedant, contact toxicity, and oviposition deterrent activities against P. xylostella .
    Phyllostine
  • HY-135450
    Dimefluthrin

    		Insecticide Cholinesterase (ChE) Infection Neurological Disease
    Dimefluthrin is an insecticide. Dimefluthrin exhibits contact toxicity against large red imported fire ant workers. Dimefluthrin undergoes horizontal transfer among red imported fire ant workers, causing secondary mortality in recipient workers. Dimefluthrin is a neurodevelopmental toxicant, which can reduces acetylcholinesterase activity, impairing neurotransmitter .
    Dimefluthrin
  • HY-W015616R
    Benzylacetone (Standard)

    4-Penylbutan-2-one (Standard)

    		 Tyrosinase Reference Standards Infection Metabolic Disease
    Benzylacetone (4-Penylbutan-2-one) (Standard) is the analytical standard of Benzylacetone (HY-W015616). This product is intended for research and analytical applications. Benzylacetone is an aromatic compound. Benzylacetone is a mushroom tyrosinase inhibitor with an IC50 of 2.8 mM, a Ki of 1.25 mM for monophenolase and an IC50 of 0.6 mM, a Ki of 0.39 mM for diphenolase. Benzylacetone inhibits free mushroom tyrosinase and enzyme-substrate complex. Benzylacetone acts as an appetite enhancer via olfactory stimulation, reduces spontaneous locomotor activity, induces weight gain. Benzylacetone exhibits repellent, fumigant, and contact toxicity against Tribolium castaneum adults .
    Benzylacetone (Standard)

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