2-Dodecanone
Based on 1 Customer Validation
2-Dodecanone is an insecticide with repellent activity against specific insect species. 2-Dodecanone exhibits contact toxicity against adult Tribolium castaneum, Lasioderma serricorne and Liposcelis bostrychophila. 2-Dodecanone shows repellent effects against adult Lasioderma serricorne.
For research use only. We do not sell to patients.
- Purity: 99.92%
- CAS No.: 6175-49-1
- Formula: C12H24O
- Molecular Weight:184.32
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Storage:Pure form -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Bioactive Compound Library Max
HY-L181
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Bioactive Compound Library
HY-L001
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Anti-Infection Compound Library
HY-L002
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Lipid Compound Library
HY-L043
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Human Metabolite Library
HY-L123
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MCE Bioactive Compound Library
HY-L001V
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Flavor Compound Library
HY-L202
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High-Throughput Bioactive Compound Library
HY-L205
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Mass Spectrometry Human Metabolite Library
HY-L215
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Chinese Baijiu Compound Library
HY-L241
Biological Activity
2-Dodecanone ( 24 h) shows significant contact toxicity against Tribolium castaneum (LD50 = 5.21 μg/adult), Lasioderma serricorne (LD50 = 2.54 μg/adult), and Liposcelis bostrychophila (LD50 = 23.41 μg/cm2) adults[1].
2-Dodecanone (24 h) exhibits fumigant toxicity against Tribolium castaneum (LC50 = 30.39 mg/L air), Lasioderma serricorne (LC50 = 7.48 mg/L air), and Liposcelis bostrychophila (LC50 = 0.82 mg/L air) adults[1].
2-Dodecanone (3.15-78.63 nL/cm2; 2-4 h) has beneficial repellent effects on Lasioderma serricorne adults[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 6175-49-1
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Appearance Liquid (Density: 0.823±0.06 g/cm3)
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Molecular Weight 184.32
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Formula C12H24O
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Color Colorless to light yellow
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SMILES
CC(CCCCCCCCCC)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (542.53 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: 5 mg/mL (27.13 mM); Suspended solution; Need ultrasonic
This protocol yields a suspended solution of 5 mg/mL. Suspended solution can be used for oral and intraperitoneal injection.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (50.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: 5 mg/mL (27.13 mM); Suspended solution; Need ultrasonic
This protocol yields a suspended solution of 5 mg/mL. Suspended solution can be used for oral and intraperitoneal injection.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (50.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (267 KB)
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SDS (458 KB)
- English - EN (458 KB)
- Français - FR (458 KB)
- Deutsch - DE (458 KB)
- Norwegian - NO (458 KB)
- Español - ES (458 KB)
- Swedish - SV (458 KB)
- Italian - IT (458 KB)
- Korean - KR (458 KB)
- Portuguese - PT (458 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.4253 mL | 27.1267 mL | 54.2535 mL | 135.6337 mL |
| 5 mM | 1.0851 mL | 5.4253 mL | 10.8507 mL | 27.1267 mL | |
| 10 mM | 0.5425 mL | 2.7127 mL | 5.4253 mL | 13.5634 mL | |
| 15 mM | 0.3617 mL | 1.8084 mL | 3.6169 mL | 9.0422 mL | |
| 20 mM | 0.2713 mL | 1.3563 mL | 2.7127 mL | 6.7817 mL | |
| 25 mM | 0.2170 mL | 1.0851 mL | 2.1701 mL | 5.4253 mL | |
| 30 mM | 0.1808 mL | 0.9042 mL | 1.8084 mL | 4.5211 mL | |
| 40 mM | 0.1356 mL | 0.6782 mL | 1.3563 mL | 3.3908 mL | |
| 50 mM | 0.1085 mL | 0.5425 mL | 1.0851 mL | 2.7127 mL | |
| 60 mM | 0.0904 mL | 0.4521 mL | 0.9042 mL | 2.2606 mL | |
| 80 mM | 0.0678 mL | 0.3391 mL | 0.6782 mL | 1.6954 mL | |
| 100 mM | 0.0543 mL | 0.2713 mL | 0.5425 mL | 1.3563 mL |
2-Dodecanone Related Classifications
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