130 Results for "

Cys253

" in MedChemExpress (MCE) Product Catalog:
Products (130)

130 Results for "Cys253" in MCE Product Catalog:

16
16 Publications Verification
Cat. No.: HY-P0036
CAS No.: 83150-76-9
Synonyms: SMS 201-995
Octreotide (SMS 201-995) is a somatostatin receptor agonist and synthetic octapeptide endogenous somatostatin analogue. Octreotide (SMS 201-995) can bind to the somatostatin receptor and mainly subtypes 2, 3, and 5, increases Gi activity, and reduces intracellular cAMP production. Octreotide (SMS 201-995) has antitumor activity, mediates apoptosis and may also be used in disease studies in acromegaly .
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16
16 Publications Verification
Cat. No.: HY-17365
CAS No.: 79517-01-4
Synonyms: SMS 201-995 acetate
Octreotide acetate, a long-acting synthetic analog of native somatostatin, inhibits growth hormone, glucagon, and insulin more potently.
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3
3 Cited Publications
Cat. No.: HY-P1036
CAS No.: 206645-99-0
Target:  

Complement System

Research Areas:  

Others

Compstatin, a 13-residue cyclic peptide, is a potent inhibitor of the complement system C3 with species specificity. Compstatin binds to baboon C3 and is resistant to proteolytic cleavage in baboon blood (similar to humans). Compstatin inhibits only the activation of primates’ complement system. Compstatin exhibits IC50 values of 63 μM and 12 μM for classical and alterative complement pathway, respectively .
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3
3 Cited Publications
Cat. No.: HY-P0123
CAS No.: 1621717-95-0
Target:  

Peptides

Research Areas:  

Others

SPACE peptide is a skin penetrating peptide (SPPs). SPACE peptide can enhance topical delivery of a macromolecule, hyaluronic acid .
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3
3 Cited Publications
Cat. No.: HY-P1036A
Target:  

Complement System

Research Areas:  

Others

Compstatin TFA, a 13-residue cyclic peptide, is a potent inhibitor of the complement system C3 with species specificity. Compstatin TFA binds to baboon C3 and is resistant to proteolytic cleavage in baboon blood (similar to humans). Compstatin TFA inhibits only the activation of primates’ complement system. Compstatin TFA exhibits IC50 values of 63 μM and 12 μM for classical and alterative complement pathway, respectively .
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2
2 Cited Publications
Cat. No.: HY-P0062B
CAS No.: 914454-03-8
Synonyms: SNX-111 acetate
Ziconotide acetate (SNX-111 acetate), a peptide, is a potent and selective block of N-type calcium channels antagonist. Ziconotide acetate reduces synaptic transmission, and can be used for chronic pain research .
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2
2 Cited Publications
Cat. No.: HY-P0173A
CAS No.: 163515-35-3
Chlorotoxin is a 36 amino-acid peptide from the venom of the Israeli scorpion Leiurus quinquestriatus with anticancer activity. Chlorotoxin is a chloride channel blocker.
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2
2 Cited Publications
Cat. No.: HY-P0173B
Chlorotoxin TFA is a peptide isolated from the venom of the scorpion Leiurus quinquestriatus, acts as a chloride channel blocker . Anti-cancer activity .
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2
2 Cited Publications
Cat. No.: HY-108814A
Purity:  97.69%
Synonyms: DX-88 TFA
Target:  

Kallikrein

Research Areas:  

Cardiovascular Disease

Ecallantide (DX-88) TFA is a specific recombinant plasma kallikrein inhibitor. Ecallantide inhibits the production of bradykinin. Ecallantide may be used to prevent acute attacks of angioedema .
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2
2 Cited Publications
Cat. No.: HY-17584A
CAS No.: 851199-60-5
Target:  

Guanylate Cyclase

Research Areas:  

Cancer

Linaclotide acetate is a potent and selective guanylate cyclase C agonist; developed for the treatment of constipation-predominant irritable bowel syndrome (IBS-C) and chronic constipation.
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1
1 Cited Publications
Cat. No.: HY-P1932
CAS No.: 186901-48-4
Cortistatin-14 is a neuropeptide that shares structural similarities with somatostatin, working by binding to somatostatin receptors (sst1-sst5). Cortistatin-14 (TFA) has anticonvulsant, neuroprotective effects, and significant anti-inflammatory properties .
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1
1 Cited Publications
Cat. No.: HY-P1464
CAS No.: 124447-81-0
Synonyms: Amylin (rat)
Target:  

Amylin Receptor

Research Areas:  

Metabolic Disease

Amylin, amide, rat is a potent and high affinity ligand of Amylin receptor AMY1 and AMY3 receptors and variably of AMY2 receptors; binding studies are generally used for the latter receptor.
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1
1 Cited Publications
Cat. No.: HY-P1548
CAS No.: 101462-82-2
Synonyms: Human β-CGRP; CGRP-II (Human)
β-CGRP, human (Human β-CGRP) is one of calcitonin peptides, acts via the complex of calcitonin-receptor-like receptor (CRLR) and receptor-activity-modifying protein (RAMP), with IC50s of 1 nM and 300 nM for CRLR/RAMP1 and CRLR/RAMP2 in cells .
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1
1 Cited Publications
Cat. No.: HY-P4058
CAS No.: 83652-28-2
Synonyms: CGRP free acid
Target:  

CGRP Receptor

Research Areas:  

Neurological Disease

Calcitonin gene-related peptide (CGRP) free acid is a 37-amino acid neuropeptide, which represents the deamidated form of α-CGRP (human) (HY-P1071). Calcitonin gene-related peptide free acid is produced in the central and peripheral nervous systems of rats, and localizes to specific sensory, integrative and motor neuron systems, including those involved in nociception/thermoreception, feeding behavior, olfaction and visceral motor functions .
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1
1 Cited Publications
Cat. No.: HY-P0061A
CAS No.: 849479-74-9
Synonyms: RC-160 acetate; BMY-41606 acetate
Target:  

Neurokinin Receptor

Research Areas:  

Cancer

Vapreotide acetate (RC-160 acetate; BMY-41606 acetate) is a neurokinin-1 (NK1) receptor antagonist, with an IC50 of 330 nM.
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1
1 Cited Publications
Cat. No.: HY-P1548A
Synonyms: Human β-CGRP TFA; CGRP-II (Human) TFA
β-CGRP, human TFA (Human β-CGRP TFA) is one of calcitonin peptides, acts via the complex of calcitonin-receptor-like receptor (CRLR) and receptor-activity-modifying protein (RAMP), with IC50s of 1 nM and 300 nM for CRLR/RAMP1 and CRLR/RAMP2 in cells .
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1
1 Cited Publications
Cat. No.: HY-P1913A
Synonyms: CGRP II (rat) TFA
Target:  

CGRP Receptor

Research Areas:  

Cardiovascular Disease

Calcitonin Gene Related Peptide II rat TFA, a CGRP receptor activator, is a potent and long-lasting vasodilator. Calcitonin Gene Related Peptide II rat TFA can be used in the research of cardiovascular diseases .
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1
1 Cited Publications
Cat. No.: HY-P0061
CAS No.: 103222-11-3
Synonyms: RC160; BMY 41606
Target:  

Neurokinin Receptor

Research Areas:  

Cancer

Vapreotide is a neurokinin-1 (NK1) receptor antagonist, with an IC50 of 330 nM.
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1
1 Cited Publications
Cat. No.: HY-P1932A
Cortistatin-14 (TFA), a neuropeptide have structural similarity to somatostatin-14, binds and exerts its function via the somatostatin receptors (sst1-sst5). Cortistatin-14 (TFA) shows anticonvulsive, neuroprotective effect and remarkable anti-inflammatory properties .
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1
1 Cited Publications
Cat. No.: HY-P1682
CAS No.: 1051366-32-5
Synonyms: POL6326
Target:  

CXCR Arrestin

Research Areas:  

Cancer

Balixafortide (POL6326) is a potent, selective, well-tolerated peptidic CXCR4 antagonist with an IC50 < 10 nM. Balixafortide shows 1000-fold selective for CXCR4 than a large panel of receptors including CXCR7. Balixafortide blocks β-arrestin recruitment and calcium flux with IC50s < 10 nM. Balixafortide is also a potent hematopoietic stem and progenitor cell (HSPC) mobilizing agent. Anti-cancer effects .
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