Search Result

Results for "

DES

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Dihydroceramide Desaturase 1 (DES1) (2) 5-HT Receptor (1) Adrenergic Receptor (1) Androgen Receptor (1) Angiotensin Receptor (1) Antibiotic (1) Apoptosis (2) Autophagy (2) Bacterial (3) Biochemical Assay Reagents (4) Bombesin Receptor (1) Bradykinin Receptor (11) Drug Metabolite (2) Environmental Pollutants (1) Estrogen Receptor/ERR (2) Fluorescent Dye (1) GCGR (5) GHSR (2) GnRH Receptor (10) HIV (1) HIV Protease (1) Integrin (1) Isotope-Labeled Compounds (5) Natriuretic Peptide Receptor (NPR) (1) Neprilysin (1) Neuropeptide B/W Receptor (1) Opioid Receptor (1) Orphan Receptor (1) Oxytocin Receptor (1) PROTAC Linkers (2) Reference Standards (1) Ser/Thr Protease (1) Small Interfering RNA (siRNA) (3) Somatostatin Receptor (1) Vasopressin Receptor (2)
By Research Areas:	Cancer (9) Cardiovascular Disease (8) Endocrinology (12) Infection (2) Inflammation/Immunology (12) Metabolic Disease (14) Neurological Disease (5)
Oligonucleotides:	Rat Pre-designed siRNA Sets (1) Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (1) siRNAs (3)

Inhibitors & Agonists

Fluorescent Dyes

Biochemical Assay Reagents

Peptides

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

Diethylstilbestrol 3 Publications Verification	Estrogen Receptor/ERR Apoptosis Autophagy	Endocrinology Cancer
Diethylstilbestrol is a non-steroidal female hormone that has oral activity and can act on menopausal and postmenopausal disorders. Diethylstilbestrol can induce DNA oxidation and Apoptosis of spermatogonial stem cells. Diethylstilbestrol can induce thymocyte Autophagy Diethylstilbestrol is a 11β-hydroxysteroid dehydrogenase 2 (HSD11B2) inhibitor. .

*[Des-Arg9]-Bradykinin acetate* 1 Publications Verification	Bradykinin Receptor	Inflammation/Immunology Endocrinology
[Des-Arg9]-Bradykinin acetate is a Bradykinin B₁ receptor agonist that displays selectivity for B₁ over B₂ receptors.

*ANP [Des18-22] 4-23 amide (rat)*	Natriuretic Peptide Receptor (NPR)	Cardiovascular Disease
ANP [Des18-22] 4-23 amide rat is a polypeptide fragment of rat atrial natriuretic peptide (ANP) that specifically binds NPR-C .

PR280	Dihydroceramide Desaturase 1 (DES1)	Neurological Disease Metabolic Disease Cancer
PR280 is a dihydroceramide desaturase 1 (Des1) inhibitor with an IC₅₀ of 700 nM. PR280 is used for the research of metabolic diseases, cancers, and neurodegenerative diseases .

des-Gln14-Ghrelin 1 Publications Verification	GHSR	Metabolic Disease
des-Gln14-Ghrelin is a second endogenous ligand for the growth hormone secretagogue receptor. a). des-Gln14-ghrelin potently induces increases in [Ca ²⁺]i in CHO-GHSR62 cells, with an EC₅₀ of 2.4 nM .

*(Des-Pyr1)-LHRH*	GnRH Receptor	Others
(Des-Pyr1)-LHRH is a Polypeptide Internal Standard, identical to (Des-Pyr1)-GnRH, which can be identified through peptide screening. Peptide screening is a research tool that mainly collects active polypeptides via immunoassays. It can be applied to protein interaction, functional analysis, epitope screening, especially in the field of active molecule research and development. (Des-Pyr1)-LHRH can serve as an internal standard (ISTD) for mass spectrometry analysis .

*(Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH* 1 Publications Verification Surfagon	GnRH Receptor	Others
(Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH (Surfagon, Mwt 1167.34 Da) is an agonist of gonadotropin-releasing hormone (GnRH). (Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH can be used as an internal standard for the LC-MS analysis of leuprorelide acetate. (Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH has potential applications in biochemical analysis and fertility .

Umirolimus	Bacterial	Inflammation/Immunology
Umirolimus, a macrocyclic triene lactone Rapamycin derivative, is powerful immunosuppressant and anti-inflammatory agent. Umirolimus has highly lipophilicity and can be used agent-eluting stent (DES) applications .

*Lys-(Des-Arg9,Leu8)-Bradykinin*	Bradykinin Receptor	Inflammation/Immunology
Lys-(Des-Arg9,Leu8)-Bradykinin is a selective bradykinin B1 receptor (BDKRB1) antagonist. Lys-(Des-Arg9,Leu8)-Bradykinin inhibits local inflammatory edema. Lys-(Des-Arg9,Leu8)-Bradykinin induces the production of systemic acute-phase proteins. Lys-(Des-Arg9,Leu8)-Bradykinin is applicable to research related to peptidoglycan-polysaccharide-induced acute arthritis .

*[Des-His1,Glu9]-Glucagon amide TFA*	GCGR	Metabolic Disease
[Des-His1,Glu9]-Glucagon amide TFA is a potent and peptide antagonist of the glucagon receptor, with a pA₂ of 7.2. [Des-His1,Glu9]-Glucagon amide TFA is potentially useful in the study of the pathogenesis of diabetes .

*Sar-[D-Phe8]-des-Arg9-Bradykinin*	Bradykinin Receptor	Inflammation/Immunology Endocrinology
Sar-[D-Phe8]-des-Arg9-Bradykinin is a agonist of B1 receptor. Sar-[D-Phe8]-des-Arg9-Bradykinin selectively amplifies the contractile response when incubation with human recombinant interleukin-1 β (IL-1 β) in rabbit aortic rings .

Mepiquat chloride N,N-Dimethylpiperidinium chloride; PIX	Environmental Pollutants Biochemical Assay Reagents	Others
Mepiquat chloride (N,N-Dimethylpiperidinium chloride) is a systemic plant growth regulator. Mepiquat chloride reduces the activity of RuBP carboxylase. Mepiquat chloride decreases plant height, total length of vegetative and fruiting branches, and total leaf area of cotton. Mepiquat chloride reduces the net photosynthetic rate of cotton leaves. Mepiquat chloride promotes starch accumulation in cotton leaves without altering sucrose content .

*[Des-His1,Glu9]-Glucagon amide*	GCGR	Metabolic Disease
[Des-His1,Glu9]-Glucagon amide is a potent and peptide antagonist of the glucagon receptor, with a pA₂ of 7.2. [Des-His1,Glu9]-Glucagon amide is potentially useful in the study of the pathogenesis of diabetes .

Dimethyl Citric acid 1 Publications Verification	Others	Others
Dimethylurea/citric acid is a highly efficient deep eutectic solvent (DES). Dimethylurea/citric acid can be used as a catalyst and a green reaction medium for the synthesis of bis(indolyl)methanes, quinolines and aryl-4, 5-diphenyl-1H-imidazoles.

*(D-Phe6,Leu-NHEt13,des-Met14)-Bombesin (6-14)*	Bombesin Receptor	Cancer
(D-Phe6,Leu-NHEt13,des-Met14)-Bombesin (6-14) is a bombesin (BBN) antagonist and can be used for the research of cancer .

*(d(CH2)51,Tyr(Me)2,Thr4,Orn8,des-Gly-NH29)-Vasotocin*	Oxytocin Receptor	Endocrinology
(d(CH2)51,Tyr(Me)2,Thr4,Orn8,des-Gly-NH29)-Vasotocin, an oxytocin receptor antagonist, abolishes oxytocin-enhanced inhibitory postsynaptic currents in CA1 pyramidal neurons .

Diethylstilbestrol (Standard)	Reference Standards Estrogen Receptor/ERR Apoptosis Autophagy	Endocrinology Cancer
Diethylstilbestrol (Standard) is the analytical standard of Diethylstilbestrol. This product is intended for research and analytical applications. Diethylstilbestrol (Stilbestrol) is a non-steroidal female hormone that has oral activity and can act on menopausal and postmenopausal disorders. Diethylstilbestrol can induce DNA oxidation and Apoptosis of spermatogonial stem cells. Diethylstilbestrol can induce thymocyte Autophagy Diethylstilbestrol is a 11β-hydroxysteroid dehydrogenase 2 (HSD11B2) inhibitor. .

*[Des-Pro2]-Bradykinin*	Ser/Thr Protease Others	Others
[Des-Pro2]-Bradykinin is a protease inhibitor. [Des-Pro2]-Bradykinin prevents the degradation of methionine enkephalin .

*(Des-Gly10,Des-Ser4,D-Leu6,Pro-NHEt9)-LHRH*	GnRH Receptor	Others
(Des-Gly10,Des-Ser4,D-Leu6,Pro-NHEt9)-LHRH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

Des-Arg9-[Leu8]-Bradykinin acetate	Bradykinin Receptor	Inflammation/Immunology
Des-Arg9-[Leu8]-Bradykinin acetate is potent bradykinin receptor 1 (B1R) antagonist. Des-Arg9-[Leu8]-Bradykinin acetate can be used for renal fibrosis research .

*[Des-Arg9]-Bradykinin*	Bradykinin Receptor	Inflammation/Immunology Endocrinology
[Des-Arg9]-Bradykinin is a Bradykinin (B₁) receptor agonist that displays selectivity for B₁ over B₂ receptors.

*(Des-Asp1,Ile8)-Angiotensin II*	Angiotensin Receptor	Cardiovascular Disease
(Des-Asp1,Ile8)-Angiotensin II is a peptide related to angiotensin II. (Des-Asp1,Ile8)-Angiotensin II can be used for studying the interaction between angiotensin II and its receptors .

*Lys-[Des-Arg9]Bradykinin TFA*	Bradykinin Receptor	Metabolic Disease Inflammation/Immunology
Lys-[Des-Arg9]Bradykinin TFA, a naturally occurring kinin, is a potent and highly selective bradykinin B1 receptor agonist with a K_i of 0.12 nM, 1.7 nM and 0.23 nM for human, mouse and rabbit B1 receptors, respectively. Lys-[Des-Arg9]Bradykinin TFA has low inhibitory activity on B2 receptors .

*[Des-Arg10]-HOE I40 TFA*	Bradykinin Receptor	Inflammation/Immunology Endocrinology
[Des-Arg10]-HOE I40 TFA is a potent bradykinin B1 receptor antagonist .

*(Des-Glu5)-ACTH (1-24) (human, bovine, rat)*	Androgen Receptor	Endocrinology
(Des-Glu5)-ACTH (1-24) (human, bovine, rat) is an analogue of Adrenocorticotropic hormone (ACTH; HY-106373). ACTH is a polypeptide tropic hormone produced by the anterior pituitary gland, regulating cortisol and androgen production .

*(Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH (salmon)*	GnRH Receptor	Endocrinology
(Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH (salmon) is a GnRH analog that induces ovulation and/or spawning in farmed fish .

*(Des-Gly10,D-His2,D-His(Bzl)6,Pro-NHEt9)-LHRH*	GnRH Receptor	Others
(Des-Gly10,D-His2,D-His(Bzl)6,Pro-NHEt9)-LHRH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

Bradykinin (2-9) DES-Arg1-bradykinin	Bradykinin Receptor	Cardiovascular Disease Endocrinology
Bradykinin (2-9) is an amino-truncated Bradykinin peptide. Bradykinin (2-9) is a metabolite of Bradykinin, cleaved by Aminopeptidase P.

Amino-PEG10-amine	PROTAC Linkers	Cancer
Amino-PEG10-amine, a PEG-based PROTAC linker used to combine two mono diethylstilbestrol (DES)-based ligands, provides an alternative strategy for preparing more selective and active ER antagonists for endocrine therapy of breast cancer .

610CP	Fluorescent Dye	Others
610CP is a new type of actin labeling dye. It dissolves in organic solvents. In DMSO the 610CP excitation/emission wavelength is between 609 and 634 nm. 610CP is a fluorescent dye that penetrates living cells. Upon cell entry, 610CP binds to Bromo-des-methyl-Jasplakinolide Therefore, 610CP dye can be used to stain actin fluorescence images with low background and high resolution.

Diastase, Aspergillus oryzae Maltin	Biochemical Assay Reagents	Others
Diastase, Aspergillus oryzae (Maltin) is a starch hydrolase derived from Aspergillus oryzae. Diastase, Aspergillus oryzae catalyzes starch hydrolysis through sequential stages, first producing dextrins, then glucose and maltose .

Des(benzylpyridyl) Atazanavir	HIV Protease HIV Drug Metabolite	Infection
Des(benzylpyridyl) Atazanavir (compound M1) is a N-dealkylation product of Atazanavir (HY-17367) metabolite. Atazanavir is a highly selective HIV-1 protease inhibitor. Des(benzylpyridyl) Atazanavir may contribute to the effectiveness Atazanavir but also to the toxicity and interactions. Des(benzylpyridyl) Atazanavir can be used for further research of Atazanavir effects .

*(Des-Pyr1,Des-Gly10,D-Leu6,Pro-NHEt9)-LHRH* (DES-Pyr1)-Leuprolide	GnRH Receptor	Others
(Des-Pyr1,Des-Gly10,D-Leu6,Pro-NHEt9)-LHRH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

*Lys-[Des-Arg9]Bradykinin*	Bradykinin Receptor	Metabolic Disease Inflammation/Immunology
Lys-[Des-Arg9]Bradykinin, a naturally occurring kinin, is a potent and highly selective bradykinin B1 receptor agonist with a K_i of 0.12 nM, 1.7 nM and 0.23 nM for human, mouse and rabbit B1 receptors, respectively. Lys-[Des-Arg9]Bradykinin has low inhibitory activity on B2 receptors .

Amino-PEG11-amine	PROTAC Linkers	Cancer
Amino-PEG11-amine, a PEG-based (12 units) PROTAC linker used to combine two mono diethylstilbestrol (DES)-based ligands, provides an alternative strategy for preparing more selective and active ER antagonists for endocrine therapy of breast cancer .

Des(8-14)brevinin-1PMa	Bacterial	Infection
Des(8-14)brevinin-1PMa is a host-defense peptide that exhibits antimicrobial activity against Staphylococcus aureus and Echerichia coli. Des(8-14)brevinin-1PMa also shows hemolytic activity .

Des-ethyl-carafiban	Integrin	Cardiovascular Disease
Des-ethyl-carafiban (Compound 44) is a fibrinogen receptor antagonist that can effectively inhibit platelet aggregation induced by multiple agonists. Des-ethyl-carafiban can be used in the research of thrombotic diseases .

Des-4-fluorobenzyl mosapride	5-HT Receptor	Neurological Disease
Des-4-fluorobenzyl mosapride is the primary metabolite of Mosapride (HY-B0189). Mosapride is an orally active gastroenterokinetic compound and is a 5HT4 agonist.

Des Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Des Rat Pre-designed siRNA Set A contains three designed siRNAs for Des gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

DES Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
DES Human Pre-designed siRNA Set A contains three designed siRNAs for DES gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Des Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Des Mouse Pre-designed siRNA Set A contains three designed siRNAs for Des gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

*[Des-His1,Glu9] Glucagon*	GCGR	Metabolic Disease
[Des-His1,Glu9] Glucagon is a potent glucagon receptor system peptide antagonist. [Des-His1,Glu9] Glucagon enhances the glucose-stimulated release of insulin from pancreatic islet cells. [Des-His1,Glu9] Glucagon can be used to research diabetes .

*(Des-Gly2)-Exenatide*	GCGR	Metabolic Disease
(Des-Gly2)-Exenatide is a potential impurity of Exenatide (HY-13443).

*[Des-Tyr1]-gamma-Endorphin*	Opioid Receptor	Neurological Disease
[Des-Tyr1]-gamma-Endorphin is a neuropeptide, which can be found in human cerebrospinal fluid. [Des-Tyr1]-gamma-Endorphin exhibits antidepressant efficacy, facilitates the extinction of active avoidance and attenuates the passive avoidance behavior in rats .

Cat. No.	Product Name	Type

HY-D1346

610CP	Fluorescent Dyes
610CP is a new type of actin labeling dye. It dissolves in organic solvents. In DMSO the 610CP excitation/emission wavelength is between 609 and 634 nm. 610CP is a fluorescent dye that penetrates living cells. Upon cell entry, 610CP binds to Bromo-des-methyl-Jasplakinolide Therefore, 610CP dye can be used to stain actin fluorescence images with low background and high resolution.

Cat. No.	Product Name	Type

HY-W017448

Mepiquat chloride

N,N-Dimethylpiperidinium chloride; PIX

Biochemical Assay Reagents

Mepiquat chloride (N,N-Dimethylpiperidinium chloride) is a systemic plant growth regulator. Mepiquat chloride reduces the activity of RuBP carboxylase. Mepiquat chloride decreases plant height, total length of vegetative and fruiting branches, and total leaf area of cotton. Mepiquat chloride reduces the net photosynthetic rate of cotton leaves. Mepiquat chloride promotes starch accumulation in cotton leaves without altering sucrose content .

Cat. No.	Product Name	Target	Research Area

HY-P0298A

*[Des-Arg9]-Bradykinin acetate* 1 Publications Verification	Bradykinin Receptor	Inflammation/Immunology Endocrinology
[Des-Arg9]-Bradykinin acetate is a Bradykinin B₁ receptor agonist that displays selectivity for B₁ over B₂ receptors.

HY-P1526

*ANP [Des18-22] 4-23 amide (rat)*	Natriuretic Peptide Receptor (NPR)	Cardiovascular Disease
ANP [Des18-22] 4-23 amide rat is a polypeptide fragment of rat atrial natriuretic peptide (ANP) that specifically binds NPR-C .

HY-P1366

des-Gln14-Ghrelin 1 Publications Verification	GHSR	Metabolic Disease
des-Gln14-Ghrelin is a second endogenous ligand for the growth hormone secretagogue receptor. a). des-Gln14-ghrelin potently induces increases in [Ca ²⁺]i in CHO-GHSR62 cells, with an EC₅₀ of 2.4 nM .

HY-P4463

*(Des-Pyr1)-LHRH*	GnRH Receptor	Others
(Des-Pyr1)-LHRH is a Polypeptide Internal Standard, identical to (Des-Pyr1)-GnRH, which can be identified through peptide screening. Peptide screening is a research tool that mainly collects active polypeptides via immunoassays. It can be applied to protein interaction, functional analysis, epitope screening, especially in the field of active molecule research and development. (Des-Pyr1)-LHRH can serve as an internal standard (ISTD) for mass spectrometry analysis .

HY-P0048

*(Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH* 1 Publications Verification Surfagon	GnRH Receptor	Others
(Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH (Surfagon, Mwt 1167.34 Da) is an agonist of gonadotropin-releasing hormone (GnRH). (Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH can be used as an internal standard for the LC-MS analysis of leuprorelide acetate. (Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH has potential applications in biochemical analysis and fertility .

HY-P4676

*Lys-(Des-Arg9,Leu8)-Bradykinin*	Bradykinin Receptor	Inflammation/Immunology
Lys-(Des-Arg9,Leu8)-Bradykinin is a selective bradykinin B1 receptor (BDKRB1) antagonist. Lys-(Des-Arg9,Leu8)-Bradykinin inhibits local inflammatory edema. Lys-(Des-Arg9,Leu8)-Bradykinin induces the production of systemic acute-phase proteins. Lys-(Des-Arg9,Leu8)-Bradykinin is applicable to research related to peptidoglycan-polysaccharide-induced acute arthritis .

HY-P1143A

*[Des-His1,Glu9]-Glucagon amide TFA*	GCGR	Metabolic Disease
[Des-His1,Glu9]-Glucagon amide TFA is a potent and peptide antagonist of the glucagon receptor, with a pA₂ of 7.2. [Des-His1,Glu9]-Glucagon amide TFA is potentially useful in the study of the pathogenesis of diabetes .

HY-103291

*Sar-[D-Phe8]-des-Arg9-Bradykinin*	Bradykinin Receptor	Inflammation/Immunology Endocrinology
Sar-[D-Phe8]-des-Arg9-Bradykinin is a agonist of B1 receptor. Sar-[D-Phe8]-des-Arg9-Bradykinin selectively amplifies the contractile response when incubation with human recombinant interleukin-1 β (IL-1 β) in rabbit aortic rings .

HY-P4409

*(Des-Ala3)-GHRP-2*	Peptides	Others
(Des-Ala3)-GHRP-2 is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P1143

*[Des-His1,Glu9]-Glucagon amide*	GCGR	Metabolic Disease
[Des-His1,Glu9]-Glucagon amide is a potent and peptide antagonist of the glucagon receptor, with a pA₂ of 7.2. [Des-His1,Glu9]-Glucagon amide is potentially useful in the study of the pathogenesis of diabetes .

HY-P4541

*(D-Phe6,Leu-NHEt13,des-Met14)-Bombesin (6-14)*	Bombesin Receptor	Cancer
(D-Phe6,Leu-NHEt13,des-Met14)-Bombesin (6-14) is a bombesin (BBN) antagonist and can be used for the research of cancer .

HY-P4397

*(d(CH2)51,Tyr(Me)2,Thr4,Orn8,des-Gly-NH29)-Vasotocin*	Oxytocin Receptor	Endocrinology
(d(CH2)51,Tyr(Me)2,Thr4,Orn8,des-Gly-NH29)-Vasotocin, an oxytocin receptor antagonist, abolishes oxytocin-enhanced inhibitory postsynaptic currents in CA1 pyramidal neurons .

HY-P2828

*[Des-Pro2]-Bradykinin*	Ser/Thr Protease Peptides	Others
[Des-Pro2]-Bradykinin is a protease inhibitor. [Des-Pro2]-Bradykinin prevents the degradation of methionine enkephalin .

HY-P4440

*(Des-Gly10,Des-Ser4,D-Leu6,Pro-NHEt9)-LHRH*	GnRH Receptor	Others
(Des-Gly10,Des-Ser4,D-Leu6,Pro-NHEt9)-LHRH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P3209

Des-Arg9-[Leu8]-Bradykinin acetate	Bradykinin Receptor	Inflammation/Immunology
Des-Arg9-[Leu8]-Bradykinin acetate is potent bradykinin receptor 1 (B1R) antagonist. Des-Arg9-[Leu8]-Bradykinin acetate can be used for renal fibrosis research .

HY-P0298

*[Des-Arg9]-Bradykinin*	Bradykinin Receptor	Inflammation/Immunology Endocrinology
[Des-Arg9]-Bradykinin is a Bradykinin (B₁) receptor agonist that displays selectivity for B₁ over B₂ receptors.

HY-P11363

*(Des-Asp1,Ile8)-Angiotensin II*	Angiotensin Receptor	Cardiovascular Disease
(Des-Asp1,Ile8)-Angiotensin II is a peptide related to angiotensin II. (Des-Asp1,Ile8)-Angiotensin II can be used for studying the interaction between angiotensin II and its receptors .

HY-103295A

*Lys-[Des-Arg9]Bradykinin TFA*	Bradykinin Receptor	Metabolic Disease Inflammation/Immunology
Lys-[Des-Arg9]Bradykinin TFA, a naturally occurring kinin, is a potent and highly selective bradykinin B1 receptor agonist with a K_i of 0.12 nM, 1.7 nM and 0.23 nM for human, mouse and rabbit B1 receptors, respectively. Lys-[Des-Arg9]Bradykinin TFA has low inhibitory activity on B2 receptors .

HY-P5518A

*[Des-Arg10]-HOE I40 TFA*	Bradykinin Receptor	Inflammation/Immunology Endocrinology
[Des-Arg10]-HOE I40 TFA is a potent bradykinin B1 receptor antagonist .

HY-P4504

*(Des-Thr7)-Glucagon*	Peptides	Others
(Des-Thr7)-Glucagon is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4411

*(Des-acetyl)-α-MSH* DESacetyl-α-MSH	Peptides	Others
(Des-acetyl)-α-MSH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4413

*(Des-Glu5)-ACTH (1-24) (human, bovine, rat)*	Androgen Receptor	Endocrinology
(Des-Glu5)-ACTH (1-24) (human, bovine, rat) is an analogue of Adrenocorticotropic hormone (ACTH; HY-106373). ACTH is a polypeptide tropic hormone produced by the anterior pituitary gland, regulating cortisol and androgen production .

HY-P4432

*(Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH (salmon)*	GnRH Receptor	Endocrinology
(Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH (salmon) is a GnRH analog that induces ovulation and/or spawning in farmed fish .

HY-P4441

*(Des-Gly10,D-His2,D-His(Bzl)6,Pro-NHEt9)-LHRH*	GnRH Receptor	Others
(Des-Gly10,D-His2,D-His(Bzl)6,Pro-NHEt9)-LHRH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P1490

Bradykinin (2-9) DES-Arg1-bradykinin	Bradykinin Receptor	Cardiovascular Disease Endocrinology
Bradykinin (2-9) is an amino-truncated Bradykinin peptide. Bradykinin (2-9) is a metabolite of Bradykinin, cleaved by Aminopeptidase P.

HY-P11361

Des B30 Insulin	Peptides	Metabolic Disease
Des B30 Insulin is a bioactive insulin analogue lacking the B30 amino acid residue. Des B30 Insulin can be used for the study of diabetes .

HY-P4467

*(Des-Pyr1,Des-Gly10,D-Leu6,Pro-NHEt9)-LHRH* (DES-Pyr1)-Leuprolide	GnRH Receptor	Others
(Des-Pyr1,Des-Gly10,D-Leu6,Pro-NHEt9)-LHRH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4493

*(Des-Ser3)-ACTH (1-24) (human, bovine, rat)*	Peptides	Others
(Des-Ser3)-ACTH (1-24) (human, bovine, rat) is a peptide analog of the adrenocorticotropic hormone (ACTH). ACTH stimulates the production of cortisol .

HY-103295

*Lys-[Des-Arg9]Bradykinin*	Bradykinin Receptor	Metabolic Disease Inflammation/Immunology
Lys-[Des-Arg9]Bradykinin, a naturally occurring kinin, is a potent and highly selective bradykinin B1 receptor agonist with a K_i of 0.12 nM, 1.7 nM and 0.23 nM for human, mouse and rabbit B1 receptors, respectively. Lys-[Des-Arg9]Bradykinin has low inhibitory activity on B2 receptors .

HY-P5713

Des(8-14)brevinin-1PMa	Bacterial	Infection
Des(8-14)brevinin-1PMa is a host-defense peptide that exhibits antimicrobial activity against Staphylococcus aureus and Echerichia coli. Des(8-14)brevinin-1PMa also shows hemolytic activity .

HY-P3608

*[Des-His1,Glu9] Glucagon*	GCGR	Metabolic Disease
[Des-His1,Glu9] Glucagon is a potent glucagon receptor system peptide antagonist. [Des-His1,Glu9] Glucagon enhances the glucose-stimulated release of insulin from pancreatic islet cells. [Des-His1,Glu9] Glucagon can be used to research diabetes .

HY-P4459

*(Des-Gly2)-Exenatide*	GCGR	Metabolic Disease
(Des-Gly2)-Exenatide is a potential impurity of Exenatide (HY-13443).

HY-P10498

*[Des-Tyr1]-gamma-Endorphin*	Opioid Receptor	Neurological Disease
[Des-Tyr1]-gamma-Endorphin is a neuropeptide, which can be found in human cerebrospinal fluid. [Des-Tyr1]-gamma-Endorphin exhibits antidepressant efficacy, facilitates the extinction of active avoidance and attenuates the passive avoidance behavior in rats .

HY-P1366A

des-Gln14-Ghrelin TFA	GHSR	Metabolic Disease
des-Gln14-Ghrelin TFA is a second endogenous ligand for the growth hormone secretagogue receptor. a). des-Gln14-ghrelin potently induces increases in [Ca ²⁺]i in CHO-GHSR62 cells, with an EC₅₀ of 2.4 nM .

HY-P2658

*[Des-Tyr1]-Met-Enkephalin*	Neprilysin	Others
[Des-Tyr1]-Met-Enkephalin, a tetrapeptide, is a degradationproduct of enkephalins .

HY-P3542

Des His1, Glu8 Exendin-4	GCGR	Metabolic Disease
Des His1, Glu8 Exendin-4 is a potent glucagon-like peptide-1 receptor (GLP-1-R) antagonist. Des His1, Glu8 Exendin-4 improves glucose homeostasis by regulating both insulin secretion and glucose production. Des His1, Glu8 Exendin-4 can be used for the research of type 2 diabetic and gastrointestinal .

HY-P5518

*[Des-Arg10]-HOE I40*	Bradykinin Receptor	Inflammation/Immunology Endocrinology
[Des-Arg10]-HOE I40 is a potent bradykinin B1 receptor antagonist .

HY-P4502

*(Des-Thr5)-Glucagon*	Peptides	Others
(Des-Thr5)-Glucagon is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4414

*(Des-Bromo)-Neuropeptide B (1-23) (human)*	Orphan Receptor Neuropeptide B/W Receptor	Neurological Disease
(Des-Bromo)-Neuropeptide B (1-23) (human) is an orphan G-protein coupled receptor agonist with K_is of 1.2 nM and 341 nM for GPR7 (NPBW1) and GPR8 (NPBW2), respectively .

HY-P3006

Des-Leu10-angiotensin I	Drug Metabolite	Cardiovascular Disease
Des-Leu10-angiotensin I is a nonapeptide that inhibits rabbit lung angiotensin-converting enzyme peptidyl-dipeptide hydrolase with a K_i value of 31 μM, which is generated from angiotensin I by the action of carboxypeptidase-like activities residing in the human platelet and mast cell .

HY-P3583

*(Des-Gly10,D-Arg6,Pro-NHEt9)-LHRH II (chicken)*	GnRH Receptor	Others
Des-Gly10,D-Arg6,Pro-NHEt9)-LHRH II (chicken) is an active petide. (Des-Gly10,D-Arg6,Pro-NHEt9)-LHRH II (chicken) can be used for the research of various biochemical studies .

HY-P3817

Des-[Gly77,His78] Myelin Basic Protein (68-84), bovine	Peptides	Neurological Disease
Des-[Gly77,His78] Myelin Basic Protein (68-84) is a 68-84 sequence fragment of guinea pig myelin basic protein (GPMBP). Des-[Gly77,His78] Myelin Basic Protein (68-84) regulates functionally diverse encephalitogenic and proliferative activities of experimental autoimmune encephalomyelitis (EAE)-associated T cells .

HY-P4456

*(Des-His6)-ACTH (1-24) (human, bovine, rat)*	Adrenergic Receptor	Endocrinology
(Des-His6)-ACTH (1-24) (human, bovine, rat) is an analogue of Adrenocorticotropic hormone (ACTH; HY-106373). ACTH is a polypeptide tropic hormone produced by the anterior pituitary gland, regulating cortisol and androgen production .

HY-P2088

TANDEM DES-N-tetramethyltriostin A	Antibiotic	Cancer
TANDEM (Des-N-tetramethyltriostin A) is a synthetic antibiotic drug that has the activity of inhibiting the growth of tumor cells. TANDEM can be used in combination with chemotherapy to enhance the inhibitory effect. TANDEM has shown significant inhibitory effects on a variety of cancer cell lines in in vitro experiments. The structure of TANDEM allows it to effectively target tumor cells during the inhibition process. TANDEM's mechanism of action involves interfering with cell proliferation and survival pathways .

HY-P4683A

*(Phenylac1,D-Tyr(Et)2,Lys6,Arg8,des-Gly9)-Vasopressin acetate*	Vasopressin Receptor	Cardiovascular Disease
(Phenylac1,D-Tyr(Et)2,Lys6,Arg8,des-Gly9)-Vasopressin is a potent vasopressin V1 receptor (VP V1R) antagonist. (Phenylac1,D-Tyr(Et)2,Lys6,Arg8,des-Gly9)-Vasopressin significantly decreases the mean arterial pressure (MAP) in rats .

HY-P4683

*(Phenylac1,D-Tyr(Et)2,Lys6,Arg8,des-Gly9)-Vasopressin*	Vasopressin Receptor	Cardiovascular Disease
(Phenylac1,D-Tyr(Et)2,Lys6,Arg8,des-Gly9)-Vasopressin is a potent vasopressin V1 receptor (VP V1R) antagonist. (Phenylac1,D-Tyr(Et)2,Lys6,Arg8,des-Gly9)-Vasopressin significantly decreases the mean arterial pressure (MAP) in rats .

HY-P4445

*(Des-Gly10,D-Leu6,Orn8,Pro-NHEt9)-LHRH*	GnRH Receptor	Others
(Des-Gly10,D-Leu6,Orn8,Pro-NHEt9)-LHRH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4442

*(Des-Gly10,D-His2,D-Trp6,Pro-NHEt9)-LHRH*	GnRH Receptor	Others
(Des-Gly10,D-His2,D-Trp6,Pro-NHEt9)-LHRH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4447

*(Des-Gly10,D-Pyr1,D-Leu6,Pro-NHEt9)-LHRH*	GnRH Receptor	Others
(Des-Gly10,D-Pyr1,D-Leu6,Pro-NHEt9)-LHRH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P11463

Des-threoninol-octreotide	Somatostatin Receptor	Metabolic Disease
Des-threoninol-octreotide (Compound 13) is a Somatostatin analog. Des-threoninol-octreotide inhibits cloned somatostatin receptors with IC₅₀ values of 13.62 nM, 10.63 nM, 10.95 nM for mSSTR2b, rSSTR5 and hSSTR5, respectively .

Species:	Human (2)
Tag:	His (1) Tag Free (1)
Source:	E. coli (2)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P70006

	*Desmin/DES* Protein, Human (His)** rHuDESmin/DES, His; DESmin; DES	Human	E. coli
	Desmin is a muscle-specific type III intermediate filament that is critical for muscle structural integrity. It forms myofibrils, interconnects Z-disks and strengthens muscle fibers. Desmin/DES Protein, Human (His) is the recombinant human-derived Desmin/DES protein, expressed by E. coli , with N-6*His labeled tag.

HY-P7018A

	DES1-3 IGF-I/IGF-1 Protein, Human rHuIGF-1; IGF-IA; Somatamedin C; MGF; IGF-I	Human	E. coli

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Source
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Free Sample	Yes No
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Cat. No.	Product Name	Chemical Structure

HY-122402S

Umirolimus-d5
Umirolimus-d₅ is the deuterium labeled Umirolimus (HY-122402). Umirolimus, a macrocyclic triene lactone Rapamycin derivative, is powerful immunosuppressant and anti-inflammatory agent. Umirolimus has highly lipophilicity and can be used agent-eluting stent (DES) applications .

HY-132795S

Des(1-cyclohexanol) Venlafaxine-d6
Des(1-cyclohexanol) Venlafaxine-d₆ is the deuterium labeled Des(1-cyclohexanol) Venlafaxine .

HY-W706908

Des(isopropylamino) atenolol diol-d5
Des(isopropylamino) atenolol diol-d₅ is the deuterium labeled 2-(4-(2,3-Dihydroxypropoxy)phenyl)acetamide (Atenolol Impurity) (HY-Z7632).

HY-141757S

Des-p-fluorobenzyl mosapride-d5
Des-p-fluorobenzyl mosapride-d₅ is the deuterium labeled Des-p-fluorobenzyl mosapride .

HY-132684S

*7-Benzyloxy-N-des[[2-(2-hydroxy)ethoxy]ethyl] Quetiapine-d8*
7-Benzyloxy-N-des[[2-(2-hydroxy)ethoxy]ethyl] Quetiapine-d₈ is the deuterium labeled 7-Benzyloxy-N-des[[2-(2-hydroxy)ethoxy]ethyl] Quetiapine .

Host:	Mouse (2) Rabbit (8)
Reactivity:	Human (7) Rat (5) Mouse (7)
Application:	IHC-P (7) ICC/IF (3) IP (4) WB (9) FC (1) ELISA (3)
Isotype:	IgG (8) IgG2b (2)
Conjugation:	Non-conjugated (10)
Clonality:	Monoclonal (8) Recombinant (5)
Modification:	Unmodified (8)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P86114

	Desmin Antibody (YA5806) CMD1I; CSM1; CSM2; DES; DESM_HUMAN; DESmin; FLJ12025; FLJ39719; FLJ41013; FLJ41793; Intermediate filament protein; OTTHUMP00000064865	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	Desmin Antibody (YA5806) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Desmin.

HY-P85911

	Desmin Antibody (YA5603) CMD1I; CSM1; CSM2; DES; DESM_HUMAN; DESmin; FLJ12025; FLJ39719; FLJ41013; FLJ41793; Intermediate filament protein; OTTHUMP00000064865	IHC-P, WB, ICC/IF, ELISA	Human, Mouse, Rat
	Desmin Antibody (YA5603) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to Desmin.

HY-P86054

	Desmin Antibody (YA5746) CMD1I; CSM1; CSM2; DES; DESM_HUMAN; DESmin; FLJ12025; FLJ39719; FLJ41013; FLJ41793; Intermediate filament protein; OTTHUMP00000064865	IHC-P, ELISA	Human, Mouse, Rat
	Desmin Antibody (YA5746) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to Desmin.

HY-P83490

	MLD Antibody (YA3235) MLD; DEGS; DES1; DES-1; FADS7; MIG15; DEGS-1	WB	Human
	MLD Antibody (YA3235) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MLD.

HY-P83490A

	MLD Antibody (YA3235)(PBS only) MLD; DEGS; DES1; DES-1; FADS7; MIG15; DEGS-1	WB	Human
	MLD Antibody (YA3235) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MLD.

HY-P81243

	F2 Antibody DES-gamma-carboxy (abnormal)prothrombin; DES-Gamma-carboxy-prothrombin; coagulation factor II (thrombin); Coagulation factor II; DCP; Factor II; Prepro coagulation factor II; Prothrombin; prothrombin B-chain; PT; RPRGL2; serine protease; THPH1; THRB; THRB_HUMAN; Thrombin heavy chain.	WB, IP	Human
	F2 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to F2.

HY-P82352

	Angiotensinogen Antibody (YA2097) Angiotensinogen; Serpin A8; AGT; SERPINA8; DES-Asp[1]-angiotensin II; Serine (or cysteine) proteinase inhibitor	WB, IHC-P, IP	Mouse
	Angiotensinogen Antibody (YA2097) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Angiotensinogen.

HY-P82008

	F2 Antibody (YA1753) Cf2; FII; Cf-2; DES-gamma-carboxy (abnormal)prothrombin; DES-Gamma-carboxy-prothrombin; coagulation factor II (thrombin); Coagulation factor II; DCP; Factor II; Prepro coagulation factor II; Prothrombin; prothrombin B-chain; PT; RPRGL2; serine protease; THPH1; THRB; THRB_HUMAN; Thrombin heavy chain.	WB, IHC-P	Mouse, Rat
	F2 Antibody (YA1753) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Prothrombin.

HY-P82352A

	Angiotensinogen Antibody (YA2097)(PBS only) Angiotensinogen; Serpin A8; AGT; SERPINA8; DES-Asp[1]-angiotensin II; Serine (or cysteine) proteinase inhibitor	WB, IHC-P, IP	Mouse
	Angiotensinogen Antibody (YA2097) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Angiotensinogen.

HY-P80103

	Desmin Antibody (YA477) 2 Publications Verification	WB, ICC/IF, IHC-P, FC	Human, Mouse, Rat
	Desmin Antibody (YA477) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Desmin.

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Free Sample	Yes No
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Cat. No.	Product Name		Classification

HY-RS23545

Des Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
Des Rat Pre-designed siRNA Set A contains three designed siRNAs for Des gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS03703

DES Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
DES Human Pre-designed siRNA Set A contains three designed siRNAs for DES gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS17101

Des Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Des Mouse Pre-designed siRNA Set A contains three designed siRNAs for Des gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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