ANP [Des18-22] 4-23 amide (rat)
Based on 1 Customer Validation
ANP [Des18-22] 4-23 amide rat is a polypeptide fragment of rat atrial natriuretic peptide (ANP) that specifically binds NPR-C.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza: 99.16%
- No. CAS: 111863-73-1
- Fòrmula: C64H107N25O19S2
- Peso molecular:1594.82
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Almacenamiento:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Actividad biológica
Chemical Information
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No. CAS 111863-73-1
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Appearance Solid
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Peso molecular 1594.82
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Fòrmula C64H107N25O19S2
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Color White to off-white
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SMILES
O=C([C@H](CSSC[C@H](NC([C@@H](NC(CNC([C@](NC([C@@H](NC([C@@H](NC([C@](NC([C@@H](NC(CNC(CNC1=O)=O)=O)CCCNC(N)=N)=O)([H])[C@@H](C)CC)=O)CC(O)=O)=O)CCCNC(N)=N)=O)([H])[C@@H](C)CC)=O)=O)C)=O)C(N)=O)NC([C@H](CO)NC([C@H](CO)NC([C@@H](N)CCCNC(N)=N)=O)=O)=O)N[C@H]1CC2=CC=CC=C2
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Sequence
Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Ile-Asp-Arg-Ile-Gly-Ala-Cys-NH2 (disulfide bridge:Cys4-Cys15)
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Sequence Shortening
RSSCFGGRIDRIGAC-NH2 (disulfide bridge:Cys4-Cys15)
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvente y solubilidad
DMSO : 25 mg/mL (15.68 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (276 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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Instrucciones de manejo (2659 KB)
Referencias
[1]. Nishizawa N, et al. A potent and selective natriuretic peptide receptor-3 blocker 11-mer peptide created by hybridization of musclin and atrial natriuretic peptide. Bioorg Med Chem Lett. 2017 Aug 1;27(15):3542-3545. [Content Brief]
[2]. Chen R, et al. Enrichment of transiently transfected mesangial cells by cell sorting after cotransfection with GFP. Am J Physiol. 1999 May;276(5):F777-85. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.6270 mL | 3.1352 mL | 6.2703 mL | 15.6758 mL |
| 5 mM | 0.1254 mL | 0.6270 mL | 1.2541 mL | 3.1352 mL | |
| 10 mM | 0.0627 mL | 0.3135 mL | 0.6270 mL | 1.5676 mL | |
| 15 mM | 0.0418 mL | 0.2090 mL | 0.4180 mL | 1.0451 mL |