1 Result for "

DFCI-002-06

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "DFCI-002-06" in MCE Product Catalog:

Cat. No.: HY-181050
CAS No.: 3092208-36-8
Target:  

PROTACs Src Btk Apoptosis

Research Areas:  

Cancer

DFCI-002-06 is an orally active dual-target HCK/BTK PROTAC degrader with DC₅₀ values for HCK and BTK of 1.3 and 4.5 nM respectively. DFCI-002-06 retains higher anti-tumor activity than the HCK/BTK dual-target inhibitor (HY-15805), inducing apoptosis in cancer cells. DFCI-002-06 can be used for the study of MYD88 mutant B-cell malignancies .
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