3 Results for "

Dasatinib derivative

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "Dasatinib derivative" in MCE Product Catalog:

Cat. No.: HY-176049
CAS No.: 3079237-53-6
Target:  

Drug Derivative

Research Areas:  

Neurological Disease

Dasatinib derivative 1 (2e) effectively releases NO and increases the concentration of 3′,5′-cyclic guanosine monophosphate, as well as maintains senolytic activity. Dasatinib derivative 1 (2e) can be used in the research for chronic ocular hypertension (COHT) glaucoma .
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Cat. No.: HY-176462
CAS No.: 2102305-55-3
Target:  

Drug Derivative

Research Areas:  

Cancer

Gly-Dasatinib (compound I-7-1), an amino acid analog of Dasatinib (HY-10181), is a tyrosine kinase inhibitor. Gly-Dasatinib can be used for the study of cancer .
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Cat. No.: HY-111874
CAS No.: 2222354-29-0
Target:  

SNIPERs Bcr-Abl

Research Areas:  

Cancer

SNIPER(ABL)-039, conjugating Dasatinib (ABL inhibitor) to LCL161 derivative (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of 10 nM. IC50s are 0.54 nM, 10 nM, 12 nM, and 50 nM for ABL, cIAP1, cIAP2, XIAP, respectively .
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