9 Results for "

Decanoylcarnitine

" in MedChemExpress (MCE) Product Catalog:
Products (9)

9 Results for "Decanoylcarnitine" in MCE Product Catalog:

Cat. No.: HY-113069
CAS No.: 1492-27-9
Purity:  99.72%
Decanoylcarnitine is a fatty ester lipid and an acylcarnitine derivative, which is a metabolite associated with impaired fatty acid metabolism in the elderly population .
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Cat. No.: HY-165175
CAS No.: 25518-51-8
Target:  

Drug Derivative

Research Areas:  

Metabolic Disease

(+)-Decanoylcarnitine is an (S)-acylcarnitine derivative and a potent inhibitor of carnitine-acylcarnitine translocase, with an IC50 of 5 μM. (+)-Decanoylcarnitine acts as a competitive inhibitor of long-chain acylcarnitine transferase and (-)-carnitine palmityltransferase. (+)-Decanoylcarnitine blocks hepatic fatty acid oxidation, ketogenesis, oleate-induced activation of gluconeogenesis, as well as associated changes in acetyl-CoA, citrate, redox pair ratios, flavins and pyridine nucleotides. (+)-Decanoylcarnitine reverses ketosis in vivo, enhances insulin-mediated hypoglycemic effects in anesthetized animals, and reduces plasma ketone body levels when used in combination with insulin. (+)-Decanoylcarnitine can be used in studies related to diabetic ketoacidosis .
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1 Cited Publications
Cat. No.: HY-113166
CAS No.: 25518-54-1
Purity:  99.75%
Synonyms: (-)-Lauroylcarnitine
Dodecanoylcarnitine ((-)-Lauroylcarnitine) is a medium long-chain acylcarnitine, an intermediate product in key energy metabolic pathways of fatty acid β-oxidation and amino acids catabolism. The abnormal decrease in the Dodecanoylcarnitine levels indicats that mitochondrial fuel metabolism, including fatty acid oxidation is significantly disturbed. Changes in plasma concentrations of Dodecanoylcarnitine are not only associated with type II diabetes, but also with pre-diabetes status. Dodecanoylcarnitine is present in fatty acid oxidation disorders such as long-chain acyl CoA dehydrogenase deficiency, carnitine palmitoyltransferase I/II deficiency, and is also associated with celiac disease. Dodecanoylcarnitine deomonstrates high sensitivities and specificities in predicting asthma. Combined model of Decanoylcarnitine (HY-113069), Dodecanoylcarnitine, PC (16:0/0:0), and Asp Arg Pro can be used as a potential biomarker for the diagnosis of Yin-deficiency-heat syndrome .
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Cat. No.: HY-135035
CAS No.: 3992-45-8
Purity:  ≥98.0%
Synonyms: (-)-Decanoylcarnitine
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease Cancer

Decanoyl-L-carnitine ((-)-Decanoylcarnitine) is an endogenous metabolite. Decanoyl-L-carnitine can be used as a serum metabolic biomarkers as indicators in the progression of intravenous leiomyomatosis .
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Cat. No.: HY-135035S
CAS No.: 1297655-08-3
Synonyms: (-)-Decanoylcarnitine-d3
Decanoyl-L-carnitine ((-)-Decanoylcarnitine)-d3 is deuterium labeled Decanoyl-L-carnitine (HY-135035). Decanoyl-L-carnitine is an endogenous metabolite. Decanoyl-L-carnitine can be used as a serum metabolic biomarkers as indicators in the progression of intravenous leiomyomatosis .
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Cat. No.: HY-100955
CAS No.: 18822-87-2
Target:  

Drug Intermediate

Research Areas:  

Others

DL-Decanoylcarnitine chloride is an intermediate in lipid metabolism .
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Cat. No.: HY-135035R
CAS No.: 3992-45-8
Synonyms: (-)-Decanoylcarnitine (Standard)
Decanoyl-L-carnitine ((-)-Decanoylcarnitine) (Standard) is the analytical standard of Decanoyl-L-carnitine (HY-135035). This product is intended for research and analytical applications. Decanoyl-L-carnitine is an endogenous metabolite. Decanoyl-L-carnitine can be used as a serum metabolic biomarkers as indicators in the progression of intravenous leiomyomatosis .
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Cat. No.: HY-135035S1
Synonyms: (-)-Decanoylcarnitine-d19
Decanoyl-L-carnitine-d19 ((-)-Decanoylcarnitine-d19> is the deuterium labeled Decanoyl-L-carnitine (HY-135035). Decanoyl-L-carnitine ((-)-Decanoylcarnitine) is an endogenous metabolite. Decanoyl-L-carnitine can be used as a serum metabolic biomarkers as indicators in the progression of intravenous leiomyomatosis.
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Cat. No.: HY-113166R
CAS No.: 25518-54-1
Synonyms: (-)-Lauroylcarnitine (Standard)
Dodecanoylcarnitine (Standard) is the analytical standard of Dodecanoylcarnitine (HY-113166). This product is intended for research and analytical applications. Dodecanoylcarnitine ((-)-Lauroylcarnitine) is a medium long-chain acylcarnitine, an intermediate product in key energy metabolic pathways of fatty acid β-oxidation and amino acids catabolism. The abnormal decrease in the Dodecanoylcarnitine levels indicats that mitochondrial fuel metabolism, including fatty acid oxidation is significantly disturbed. Changes in plasma concentrations of Dodecanoylcarnitine are not only associated with type II diabetes, but also with pre-diabetes status. Dodecanoylcarnitine is present in fatty acid oxidation disorders such as long-chain acyl CoA dehydrogenase deficiency, carnitine palmitoyltransferase I/II deficiency, and is also associated with celiac disease. Dodecanoylcarnitine deomonstrates high sensitivities and specificities in predicting asthma. Combined model of Decanoylcarnitine (HY-113069), Dodecanoylcarnitine, PC (16:0/0:0), and Asp Arg Pro can be used as a potential biomarker for the diagnosis of Yin-deficiency-heat syndrome .
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