29 Results for "

EphA4

" in MedChemExpress (MCE) Product Catalog:
Products (29)

29 Results for "EphA4" in MCE Product Catalog:

  • Isoforms Recommended:
  • Recombinant Proteins Recommended:
3
3 Cited Publications
Cat. No.: HY-P2264
CAS No.: 676657-00-4
Target:  

Ephrin Receptor

Research Areas:  

Inflammation/Immunology

KYL peptide, an antagonistic peptide, selectively targets EphA4 receptor (IC50:4.22 μM, Kd:1.3 μM). KYL peptide binds to the ligand-binding domain of EphA4, effectively alleviates Aβ-induced synaptic dysfunction and synaptic plasticity defects in AD mice. KYL peptide can promote nerve regeneration after injury and modulating immune responses .
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2
2 Cited Publications
Cat. No.: HY-N0387
CAS No.: 76-66-4
Rhyncholphylline is an alkaloid compound isolated from Uncaria rhynchophyllum. Rhyncholphylline is an EphA4 inhibitor. It has high biological activity and is widely used in anti-inflammatory, neuroprotective and other research. .
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1
1 Cited Publications
Cat. No.: HY-P0177
CAS No.: 2034159-30-1
Target:  

Ephrin Receptor

Research Areas:  

Metabolic Disease

123C4 is a potent, selective and competitive agonist of the receptor tyrosine kinase EPHA4, with a Ki value of 0.65 μM .
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1
1 Cited Publications
Cat. No.: HY-P10579
CAS No.: 2225868-19-7
Target:  

Ephrin Receptor

Research Areas:  

Cancer

123B9, a tumor-homing agent, is a potent and selective EphA2 agonist with a Kd value of 4.0 μM. 123B9 selectively targets the EphA2 tyrosine kinase receptor ligand-binding domain. 123B9 does not appreciably inhibit the ligand binding domains of the most closely related EphA3 and EphA4 receptors .
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Cat. No.: HY-W078239
CAS No.: 313701-92-7
Target:  

Ephrin Receptor

Research Areas:  

Cancer

EPHA4 antagonist-1 (Compound 2) is an EphA4 receptor antagonist. EPHA4 antagonist-1 is also an EphA2 receptor antagonist. EPHA4 antagonist-1 inhibits ephrin-A5 AP binding to EphA4 Fc receptor, with an IC50 of 10 μM .
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Cat. No.: HY-P11243
Target:  

Ephrin Receptor

Research Areas:  

Neurological Disease

EphA4 agonist compound 23 is a novel EphA4 agonist peptide mimic. EphA4 agonist compound 23 exhibits high affinity, high selectivity, and significant receptor activation ability. EphA4 agonist compound 23 is commonly used in the study of neurodegenerative diseases .
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Cat. No.: HY-P11035
Target:  

Ephrin Receptor

Research Areas:  

Neurological Disease Cancer

APY-d3 is a highly selective EphA4 receptor inhibitor, with an IC50 value of 17-56 nM for human EphA4, an IC50 value of 20 nM for mouse EphA4, and a Kd value of 138 nM for EphA4-LBD. APY-d3 binds to EphA4, blocks its interaction with ephrin ligands, inhibits tyrosine phosphorylation of EphA4, prevents growth cone collapse, and does not induce EphA4 phosphorylation in primary cortical neurons. APY-d3 adopts a β-hairpin conformation stabilized by an N-terminal to C-terminal disulfide bond. APY-d3 can be used in research related to amyotrophic lateral sclerosis, Alzheimer's disease, stroke, neurodegenerative diseases and cancer [4].
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Cat. No.: HY-RS04428
Research Areas:  

Others

EPHA4 Human Pre-designed siRNA Set A contains three designed siRNAs for EPHA4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS17700
Research Areas:  

Others

Epha4 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Epha4 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-146375
CAS No.: 2938227-14-4
Target:  

Ephrin Receptor

Research Areas:  

Cancer

UniPR505 (Compound 14) is an EphA2 antagonist with an IC50 of 0.95 µM. UniPR505 displays anti-angiogenic properties .
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Cat. No.: HY-P11244
CAS No.: 2866306-73-0
Target:  

Ephrin Receptor

Research Areas:  

Neurological Disease

150D4 is an efficient, selective, and blood-brain barrier penetrable EphA4 agonist. 150D4 has excitatory activity and neuroprotective effects. 150D4 can be used for research on neurological conditions .
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Cat. No.: HY-RS24162
Research Areas:  

Others

Epha4 Rat Pre-designed siRNA Set A contains three designed siRNAs for Epha4 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-159174
EPHA2/A4/GAK-IN-1 (compound 55) is a potent inhibitor of EPHA2/EPHA4 and GAK with KD values of 180.5 nM for EPHA2 and 19.2 nM for GAK, respectively. EPHA2/GAK-IN-1 shows an extrapolated half-life time of 4.6 h in a microsomal stability assay. EPHA2/GAK-IN-1 shows antiviral activity and prevents dengue virus infection of Huh7 liver cells .
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Cat. No.: HY-P11015
Target:  

Ephrin Receptor

Research Areas:  

Cancer

(123B9)2-Motif is a selective EphA2 receptor agonist (Kd=4.9 μM) that does not bind to EphA4. (123B9)2-Motif works by inducing EphA2 receptor phosphorylation and oligomerization, thereby promoting receptor activation and internalization. (123B9)2-Motif is primarily used in targeted drug delivery studies for cancers that overexpress EphA2, such as breast cancer, to reduce circulating tumor cells and inhibit metastasis .
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Cat. No.: HY-P991974

Target:  

Ephrin Receptor

Research Areas:  

Cancer

Anti-EPHA4 Antibody is an anti-EPHA4 antibody. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-N0387R
CAS No.: 76-66-4
Rhynchophylline (Standard) is the analytical standard of Rhynchophylline. This product is intended for research and analytical applications. Rhyncholphylline is an alkaloid compound isolated from Uncaria rhynchophyllum. Rhyncholphylline is an EphA4 inhibitor. It has high biological activity and is widely used in anti-inflammatory, neuroprotective and other research. .
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Cat. No.: HY-P78293
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: Sek; Sek1; EphA4; HEK8; SEK; TYRO1; EK8
Species:  
Source:  
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Cat. No.: HY-P75238
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Ephrin type-A receptor 4; EPH-like kinase 8; EK8; EphA4; HEK8; SEK; TYRO1
Species:  
Rat
Source:  
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Cat. No.: HY-P75239
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Ephrin type-A receptor 4; EPH-like kinase 8; EK8; EphA4; HEK8; SEK; TYRO1
Species:  
Rat
Source:  
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Cat. No.: HY-P72995
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Ephrin type-A receptor 4; EPH-like kinase 8; EK8; EphA4; HEK8; SEK; TYRO1
Species:  
Source:  
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