2. Protein Tyrosine Kinase/RTK
  3. Ephrin Receptor
  4. UniPR505

UniPR505 (Compound 14) is an EphA2 antagonist with an IC50 of 0.95 µM. UniPR505 displays anti-angiogenic properties.

For research use only. We do not sell to patients.

UniPR505 Chemical Structure

UniPR505 Chemical Structure

CAS No. : 2938227-14-4

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UniPR505 Related Antibodies

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Description

UniPR505 (Compound 14) is an EphA2 antagonist with an IC50 of 0.95 µM. UniPR505 displays anti-angiogenic properties[1].

IC50 & Target

IC50: 0.95 µM (EphA2), 4.4 µM (EphA5), 4.5 µM (EphA3), 6.4 µM (EphA4), 7.7 µM (EphA8), 11 µM (EphB3), 14 µM (EphB2), 18 µM (EphA6)[1]
Molecular Weight

647.89

Formula

C39H57N3O5
CAS No.
SMILES

[H][C@]12CC[C@@]3([H])[C@]4([H])CC[C@@H]([C@]4(CC[C@]3([H])[C@]1(CC[C@H](C2)OC(NCC)=O)C)C)[C@@H](CCC(N[C@@H](CC5=CNC6=C5C=CC=C6)CC(O)=O)=O)C
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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UniPR505 Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

UniPR5052938227-14-4UniPR 505UniPR-505Ephrin Receptorglioblastomaanti-angiogenicanticancerEphA3EphA4EphA5EphA6EphA8EphB2EphB3Inhibitorinhibitorinhibit

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