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Results for "

FGF1

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Biochemical Assay Reagents (1) Caspase (1) EGFR (1) FGFR (2) mRNA (1) PDGFR (1) Small Interfering RNA (siRNA) (3) Src (1) TGF-β Receptor (1) Thymidylate Synthase (1) VEGFR (1)
By Research Areas:	Cancer (4) Cardiovascular Disease (1) Endocrinology (1) Metabolic Disease (1)
Oligonucleotides:	Rat Pre-designed siRNA Sets (1) mRNA (1) Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (1) siRNAs (3)

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Recombinant Proteins

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-100434

PD-161570	FGFR PDGFR EGFR Src TGF-β Receptor	Cardiovascular Disease Cancer
PD-161570 is a potent and ATP-competitive *human FGF-1* receptor inhibitor with an IC₅₀ of 39.9 nM and a K_i of 42 nM. PD-161570 also inhibits the PDGFR, EGFR and c-Src tyrosine kinases with IC₅₀ values of 310 nM, 240 nM, and 44 nM, respectively. PD-161570 inhibits PDGF*-stimulated autophosphorylation and FGF-1* receptor phosphorylation with IC₅₀s of 450 nM and 622 nM, respectively ^[1] . PD-161570 is also a bone morphogenetic proteins (BMPs) and TGF-β signaling inhibitor .

HY-126436D

Poly-L-ornithine hydrochloride (MW 15000-30000) L-Ornithine homopolymer hydrochloride (MW 15000-30000)	Biochemical Assay Reagents	Metabolic Disease Endocrinology
Poly-L-ornithine hydrochloride (MW 15000-30000) is a polycationic homopolymer composed of L-ornithine. Poly-L-ornithine hydrochloride (MW 15000-30000) adsorbs negatively charged species through electrostatic interactions. Poly-L-ornithine hydrochloride (MW 15000-30000) can be used as a key component of polyelectrolyte complexes to construct core-shell structure carriers to achieve controlled delivery of growth factors (such as rhBMP-2, FGF-1). Poly-L-ornithine hydrochloride (MW 15000-30000) is used in the study of diabetes and bone regeneration related diseases ^[1] .

HY-RS04886

FGF1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
FGF1 Human Pre-designed siRNA Set A contains three designed siRNAs for FGF1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

FGF1 Human Pre-designed siRNA Set A FGF1 Human Pre-designed siRNA Set A

HY-RS23045

Fgf1 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Fgf1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Fgf1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Fgf1 Rat Pre-designed siRNA Set A Fgf1 Rat Pre-designed siRNA Set A

HY-RS16610

Fgf1 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Fgf1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Fgf1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Fgf1 Mouse Pre-designed siRNA Set A Fgf1 Mouse Pre-designed siRNA Set A

HY-174712

*Human FGF1* mRNA**	mRNA	Cancer
Human FGF1 mRNA encodes the human Fibroblast growth factor 1 (FGF1) protein, a member of fibroblast growth factor (FGF) family. FGF1 functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It also acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis.

HY-149352

DG1	Thymidylate Synthase	Cancer
DG1 (Compound 8Nc) is a Thymidylate Synthase (TS) inhibitor that affects cancer angiogenesis and metabolic reprogramming in NSCLC cells. DG1 can effectively inhibit the expression of CD26, ET-1, FGF-1 and EGF. DG1 also effectively inhibits the proliferation of cancer tissue in the A549 xenograft mouse model ^[1].

HY-19891

PG545	FGFR VEGFR	Cancer
PG545 is a heparanase inhibitor and an *FGF/VEGF* inhibitor, with a K_i value of 6.1 nM against human heparanase, and K_d values of 8 nM, 390 nM, and 28.9 nM against human FGF-1, FGF-2, and VEGF, respectively. PG545 inhibits angiogenesis, tumor growth, and metastasis. PG545 is applicable in research related to melanoma and colorectal cancer ^[1].

HY-P10955

Ac-AAVALLPAVLLALLAPVAD-CHO TFA	Caspase	Others
Ac-AAVALLPAVLLALLAPVAD-CHO (TFA) is a composite of Ac-VAD-CHO. Ac-AAVALLPAVLLALLAPVAD-CHO (TFA) is a non-selective caspase inhibitor as well as a cell permeable hydrophobic sequence derived from K-FGF .

Cat. No.	Product Name	Type

HY-126436D

Poly-L-ornithine hydrochloride (MW 15000-30000) L-Ornithine homopolymer hydrochloride (MW 15000-30000)	Biochemical Assay Reagents
Poly-L-ornithine hydrochloride (MW 15000-30000) is a polycationic homopolymer composed of L-ornithine. Poly-L-ornithine hydrochloride (MW 15000-30000) adsorbs negatively charged species through electrostatic interactions. Poly-L-ornithine hydrochloride (MW 15000-30000) can be used as a key component of polyelectrolyte complexes to construct core-shell structure carriers to achieve controlled delivery of growth factors (such as rhBMP-2, FGF-1). Poly-L-ornithine hydrochloride (MW 15000-30000) is used in the study of diabetes and bone regeneration related diseases ^[1] .

Poly-L-ornithine hydrochloride (MW 15000-30000)

L-Ornithine homopolymer hydrochloride (MW 15000-30000)

Biochemical Assay Reagents

Poly-L-ornithine hydrochloride (MW 15000-30000) is a polycationic homopolymer composed of L-ornithine. Poly-L-ornithine hydrochloride (MW 15000-30000) adsorbs negatively charged species through electrostatic interactions. Poly-L-ornithine hydrochloride (MW 15000-30000) can be used as a key component of polyelectrolyte complexes to construct core-shell structure carriers to achieve controlled delivery of growth factors (such as rhBMP-2, FGF-1). Poly-L-ornithine hydrochloride (MW 15000-30000) is used in the study of diabetes and bone regeneration related diseases ^[1] .

Cat. No.	Product Name	Target	Research Area

HY-P10955

Ac-AAVALLPAVLLALLAPVAD-CHO TFA	Caspase	Others
Ac-AAVALLPAVLLALLAPVAD-CHO (TFA) is a composite of Ac-VAD-CHO. Ac-AAVALLPAVLLALLAPVAD-CHO (TFA) is a non-selective caspase inhibitor as well as a cell permeable hydrophobic sequence derived from K-FGF .

Recombinant Proteins Recommended:

FGF-1

Species:	Human (5) Mouse (2) Rat (1) Cynomolgus (1) Canine (1)
Tag:	His (3) Tag Free (7) Avi (1)
Source:	E. coli (10)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P704135

	FGF-1 Protein, Human (Biotinylated, His, Avi) rHuaFGF; HBGF-1; ECGF; FGF1; FGF-a; FGF-acidic	Human	E. coli
	FGF-1 protein complexly regulates cell survival, division, angiogenesis, differentiation, and migration. As a potent mitogen, it acts as a ligand for FGFR1 and integrins. FGF-1 Protein, Human (Biotinylated, His, Avi) is the recombinant human-derived FGF-1 protein, expressed by E. coli, with N-His and N-Avi labeled tag.

HY-P75194

	FGF-1 Protein, Canine HBGF-1; ECGF; FGF1; FGF-a; FGF-acidic	Canine	E. coli
	The FGF-1 protein is critical in cellular regulation, coordinating key processes such as cell survival, division, angiogenesis, differentiation and migration. It exhibits potent mitogenic properties in vitro and serves as a ligand for FGFR1 and integrins. FGF-1 Protein, Canine is the recombinant canine-derived FGF-1 protein, expressed by E. coli , with tag free.

HY-P76332

	FGF-1 Protein, Cynomolgus HBGF-1; ECGF; FGF1; FGF-a; FGF-acidic	Cynomolgus	E. coli
	Fibroblast growth factor 1 is a growth factor and signaling protein encoded by the FGF1 gene. FGF-1 is a ligand of FGFR1 and integrin, and plays an important role in cell survival, division, angiogenesis, differentiation, and migration. FGF-1 induces the phosphorylation and activation of FGFR1, FRS2, MAPK3/ERK1, MAPK1/ERK2, and AKT1, and also stimulates angiogenesis. FGF-1 Protein, Cynomolgus is the recombinant cynomolgus-derived FGF-1 protein, expressed by E. coli , with tag free.

HY-P704537

	FGF-1 Protein, Rat Fibroblast growth factor 1; HBGF-1; FGF1; FGF-a; FGF-acidic	Rat	E. coli
	FGF-1 Protein, Rat is the recombinant rat-derived FGF-1 protein, expressed by E. coli, with tag free tag.

HY-P7065

	FGF-1 Protein, Mouse 1 Publications Verification rMuaFGF; HBGF-1; FGF1; FGF-a; FGF-acidic	Mouse	E. coli
	FGF-1 Protein, Mouse is a growth factor and signaling protein encoded by the FGF1 gene.

HY-P7001

	FGF-1 Protein, Human 2 Publications Verification rHuaFGF; HBGF-1; ECGF; FGF1; FGF-a; FGF-acidic	Human	E. coli
	FGF-1 Protein, Human is a growth factor and signaling protein encoded by the FGF1 gene.

HY-P700282

	FGF-1 Protein, Mouse (N-His) rMuaFGF; HBGF-1; FGF1; FGF-a; FGF-acidic	Mouse	E. coli
	The FGF-1 protein plays a key role in regulating a variety of cellular processes, serving as a potent mitogen and ligand for FGFR1 and integrins. In the presence of heparin, FGF-1 binds to FGFR1, initiating dimerization and autophosphorylation, resulting in multiple signaling cascades. FGF-1 Protein, Mouse (N-His) is the recombinant mouse-derived FGF-1 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P700053AF

	*Animal-Free FGF-1* Protein, Human (His)** aFGF; HBGF-1; ECGF; FGF1; FGF-a; FGF-acidic	Human	E. coli
	FGF-1 protein complexly regulates cell survival, division, angiogenesis, differentiation, and migration. As a potent mitogen, it acts as a ligand for FGFR1 and integrins. Animal-Free FGF-1 Protein, Human (His) is the recombinant human-derived animal-FreeFGF-1 protein, expressed by E. coli , with C-His labeled tag.This product is for cell culture use only.

HY-P700289

	FGF-1 Protein, Human (154a.a) 2 Publications Verification Fibroblast Growth Factor 1; FGF-1; Acidic Fibroblast Growth Factor; aFGF; Endothelial Cell Growth Factor; ECGF; Heparin-Binding Growth Factor 1; HBGF-1; FGF1; FGFA	Human	E. coli
	FGF-1 protein complexly regulates cell survival, division, angiogenesis, differentiation, and migration. As a potent mitogen, it acts as a ligand for FGFR1 and integrins. FGF-1 Protein, Human (154a.a) is the recombinant human-derived FGF-1 protein, expressed by E. coli , with tag free.

HY-P72641

	FIBP Protein, Human Acidic fibroblast growth factor intracellular-binding protein; FGF-1 intracellular-binding protein; FIBP	Human	E. coli
	FIBP is an intracellular chaperone of acidic fibroblast growth factor (aFGF) and mediates the mitogenic effects of aFGF, affecting cell types through mitosis and inducing morphological changes and differentiation. This gene expresses two isoforms, showing potential functional diversity. FIBP Protein, Human is the recombinant human-derived FIBP protein, expressed by E. coli , with tag free.

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HY-P81685

	FGF1 Antibody (YA1430) FGF1; FGFA; Fibroblast growth factor 1; FGF-1; Acidic fibroblast growth factor; aFGF; Endothelial cell growth factor; ECGF; Heparin-binding growth factor 1; HBGF-1	WB, IHC-P	Human, Mouse, Rat
	FGF1 Antibody (YA1430) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to FGF1.