FGF-1
FGF-1, the founding acidic FGF (aFGF), is unusual among the family in binding all four signaling FGFRs and in lacking a conventional signal peptide. It is released through a non-classical export pathway involving S100A13 and synaptotagmin-1, and its activity is strongly potentiated by heparin and heparan sulfate. FGF-1 is expressed widely in brain, retina and mesenchymal tissues, where it promotes endothelial and fibroblast proliferation, angiogenesis and wound repair. A receptor-independent intracellular form modulates p53 activity. Recombinant FGF-1 is a versatile mitogen for cell culture, a positive control for pan-FGFR activation and a candidate scaffold for biomaterial-assisted tissue engineering.
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FGF-1 Protéines Recombinantes (8)
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formule: Human
- Masse moléculaire: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
