1 Result for "

FGFR-IN-8

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "FGFR-IN-8" in MCE Product Catalog:

Cat. No.: HY-150652
CAS No.: 2640217-64-5
Target:  

FGFR Apoptosis

Research Areas:  

Cancer

FGFR-IN-8 (Compound 17a) is a highly potent and orally active panFGFR inhibitor against wild-type and mutant FGFRs. FGFR-IN-8 shows inhibition with IC50 values of <0.5, 189.1, <0.5, 22.6, <0.5 and 7.30 nM against FGFR1, V564F-FGFR2, N549H-FGFR2, V555M-FGFR3, FGFR3 and FGFR4, respectively. GFR-IN-8 induces cancer cell apoptosis and shows anticancer activities .
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