1 Result for "

FLT3-IN-11

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "FLT3-IN-11" in MCE Product Catalog:

Cat. No.: HY-143894
CAS No.: 2499966-50-4
Target:  

FLT3

Research Areas:  

Cancer

FLT3-IN-11 (compound 30) is a potent, selective and orally active FLT3 kinase inhibitor with IC50s of 7.22 nM and 4.95 nM for wild-type FLT3 and FLT3-D835Y, respectively. FLT3-IN-11 high selectivity for FLT3 over c-KIT (>1000-fold). FLT3-IN-11has excellent anti-acute myeloid leukemia (AML) activity (MV4-11 cells, IC50 of 3.2 nM) .
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