34 Results for "

FcRγIIIa

" in MedChemExpress (MCE) Product Catalog:
Products (34)

34 Results for "FcRγIIIa" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-109010
CAS No.: 1353552-97-2
Purity:  98.08%
Synonyms: HM71224; LY3337641
Research Areas:  

Metabolic Disease

Poseltinib (HM71224) is an orally active, selective, irreversible small molecule Bruton tyrosine kinase (BTK) inhibitor. With an IC50 of 1.95 nM. Poseltinib effectively inhibits the signaling mediated by B cell receptors (BCR), Fc receptors (FcR), and Toll-like receptors (TLR). Poseltinib has anti-inflammatory activity and can be used in the research of rheumatoid arthritis .
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1
1 Cited Publications
Cat. No.: HY-N6742
CAS No.: 7184-60-3
Synonyms: Treponemycin
Borrelidin (Treponemycin) is a bacterial and eukaryal threonyl-tRNA synthetase inhibitor which is a nitrile-containing macrolide antibiotic isolated from Streptomyces rochei . Borrelidin is an inhibitor of Cdc28/Cln2 of the budding yeast, with an IC50 of 24 μM . Borrelidin is a potent angiogenesis inhibitor, with an IC50 of 0.8 nM. Borrelidin induces apoptosis in the tube-forming cells . Borrelidin has strong antimalarial activities, with IC50s of 1.9 nM and 1.8 nM against K1 and FCR3 strains of Plasmodium falciparum, respectively .
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1
1 Cited Publications
Cat. No.: HY-P99437
CAS No.: 2367012-88-0
Synonyms: KN-026

Target:  

EGFR

Research Areas:  

Cancer

Anbenitamab (KN-026) is a bispecific antibody simultaneously targeting extracellular domains II and IV of human HER2. Anbenitamab blocks both ligand-dependent and ligand-independent HER2 signaling pathways. Anbenitamab mediates antibody-dependent cellular cytotoxicity (ADCC) via FcγIIIa binding. Ambrinitumab can be used in research for lung cancer, HER2-positive metastatic breast cancer (MBC), gastric cancer, and gastroesophageal junction cancer .
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Cat. No.: HY-107835
CAS No.: 69770-45-2
Purity:  95.20%
Synonyms: FCR 2769
Flumethrin (FCR 2769) is a pyrethroid insecticide and acaricide . Flumethrin targets voltage-gated sodium channels and estrogen receptor α (ERα). Flumethrin induces cytotoxicity, apoptosis, genotoxicity and DNA damage in breast cancer cells by regulating the expression of BCL2, BAX, TP53 and P21 genes. Flumethrin is applicable to relevant studies on ectoparasite infections (tick and flea burdens) in dogs and cats, as well as breast cancer .
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Cat. No.: HY-P991510

Target:  

TNF Receptor

Research Areas:  

Cancer

CDX-1140 is a fully human IgG monoclonal antibody and CD40 agonist, with a Kd value of 0.01 nM against human targets. The epitope of CDX-1140 locates at CD40 CRD1 and avoids the CD40L binding site. It activates DCs and B cells, drives NF-κB reporter gene activation, exhibits agonist activity independent of FcR cross-linking, and shows a synergistic effect with recombinant CD40L . CDX-1140 does not induce systemic cytokine release, exerts direct and immune-mediated anti-tumor activity in tumor xenografts, and has favorable safety profiles. When used as a local vaccine adjuvant in combination with 6MHP+mBRAF+poly-ICLC, CDX-1140 increases the number of DC-LAMP + DCs and induces Th1 CD4 + responses in high-risk melanoma. CDX-1140 can be used in studies related to B-cell lymphoma, bladder cancer and high-risk melanoma .
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Cat. No.: HY-107835R
CAS No.: 69770-45-2
Synonyms: FCR 2769 (Standard)
Flumethrin (Standard) (FCR 2769 (Standard)) is the analytical standard of Flumethrin (HY-107835). This product is intended for research and analytical applications. Flumethrin (FCR 2769) is a pyrethroid insecticide and acaricide. Flumethrin targets voltage-gated sodium channels and estrogen receptor α (ERα). Flumethrin induces cytotoxicity, apoptosis, genotoxicity and DNA damage in breast cancer cells by regulating the expression of BCL2, BAX, TP53 and P21 genes. Flumethrin is applicable to relevant studies on ectoparasite infections (tick and flea burdens) in dogs and cats, as well as breast cancer.
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Cat. No.: HY-N10624
CAS No.: 2925302-01-6
Target:  

Parasite

Koshidacin B is an antiplasmodial cyclic tetrapeptide with antiplasmodial activity against P. falciparum FCR3 and K1 strain with IC50 values of 0.89 and 0.83 μM, respectively. Koshidacin B suppresses malaria parasites in vivo, it can be used for the research of parasites infection .
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Cat. No.: HY-170848
CAS No.: 2035422-63-8
Target:  

Parasite

Research Areas:  

Infection

Antimalarial agent 48 (Compound 15a) is a triazine-class compound with antimalarial activity, showing inhibitory concentrations of 280 nM against Plasmodium falciparum K1 and 290 nM against Plasmodium falciparum FCR3. Antimalarial agent 48 is expected to be useful for research in the field of antimalarial infections .
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Cat. No.: HY-107835S
Synonyms: FCR 2769-d5
Flumethrin-d5 (FCR 2769-d5) is the deuterium labeled Flumethrin (HY-107835). Flumethrin (FCR 2769) is a pyrethroid insecticide and acaricide . Flumethrin targets voltage-gated sodium channels and estrogen receptor α (ERα). Flumethrin induces cytotoxicity, apoptosis, genotoxicity and DNA damage in breast cancer cells by regulating the expression of BCL2, BAX, TP53 and P21 genes. Flumethrin is applicable to relevant studies on ectoparasite infections (tick and flea burdens) in dogs and cats, as well as breast cancer .
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Cat. No.: HY-P991848

Target:  

Fc Receptor (FcR)

Research Areas:  

Inflammation/Immunology

Anti-CD64 Antibody (10.1) recognizes an epitope on human CD64 (Fc_RI). Fc gamma receptors (Fc_Rs) are membrane-bound proteins which control and mediate communication of IgG antibodies within the immune system. Recommend Isotype Controls: Mouse IgG1 kappa, Isotype Control (HY-P99977) .
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Cat. No.: HY-109010R
CAS No.: 1353552-97-2
Synonyms: HM71224 (Standard); LY3337641 (Standard)
Poseltinib (Standard) is the analytical standard of Poseltinib (HY-109010). This product is intended for research and analytical applications. Poseltinib (HM71224) is an orally active, selective, irreversible small molecule Bruton tyrosine Kinase (BTK) inhibitor. With an IC50 of 1.95 nM. Poseltinib effectively inhibits the signaling mediated by B cell receptors (BCR), Fc receptors (FcR), and Toll-like receptors (TLR). Poseltinib has anti-inflammatory activity and can be used in the research of rheumatoid arthritis .
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Cat. No.: HY-P991958

Target:  

CTLA-4

Research Areas:  

Cancer

GIGA-564 is a fully human anti-CTLA4 IgG1 monoclonal antibody with a Kd of 9.8 nM. GIGA-564 binds to a unique epitope of CTLA-4, mediates FcR-dependent signaling pathways, depletes CTLA-4-highly-expressing regulatory T cells within tumors, and inhibits the proliferation of peripheral regulatory T cells. GIGA-564 exhibits anti-tumor activity in mouse models. GIGA-564 can be used for tumor research .
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Cat. No.: HY-P700302
Purity:  > 95%, as determined by Bis-Tris PAGE.
Synonyms: FCRL5; FcR-Like Protein 5; Fc Receptor Like 5; Immunoglobulin Superfamily Receptor Translocation Associated 2 (IRTA2); BXMAS1; Fc Receptor-Like 5; FCRH5; CD307e Antigen; IRTA2; PRO820; CD307e; CD307; Immune Receptor Translocation-Associated Protein 2; FcR
Species:  
Source:  
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Cat. No.: HY-P77652
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: FCRL5; FcR-Like Protein 5; Fc Receptor Like 5; Immunoglobulin Superfamily Receptor Translocation Associated 2 (IRTA2); BXMAS1; Fc Receptor-Like 5; FCRH5; CD307e Antigen; IRTA2; PRO820; CD307e; CD307; Immune Receptor Translocation-Associated Protein 2; FcR
Species:  
Source:  
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Cat. No.: HY-P703727
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FCRL5; FcR-Like Protein 5; Fc Receptor Like 5; Immunoglobulin Superfamily Receptor Translocation Associated 2 (IRTA2); BXMAS1; Fc Receptor-Like 5; FCRH5; CD307e Antigen; IRTA2; PRO820; CD307e; CD307; Immune Receptor Translocation-Associated Protein 2; FcR
Species:  
Source:  
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Cat. No.: HY-P702590
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FCRL5; FcR-Like Protein 5; Fc Receptor Like 5; Immunoglobulin Superfamily Receptor Translocation Associated 2 (IRTA2); BXMAS1; Fc Receptor-Like 5; FCRH5; CD307e Antigen; IRTA2; PRO820; CD307e; CD307; Immune Receptor Translocation-Associated Protein 2; FcR
Species:  
Source:  
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Cat. No.: HY-P703957
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: FCRL5; FcR-Like Protein 5; Fc Receptor Like 5; Immunoglobulin Superfamily Receptor Translocation Associated 2 (IRTA2); BXMAS1; Fc Receptor-Like 5; FCRH5; CD307e Antigen; IRTA2; PRO820; CD307e; CD307; Immune Receptor Translocation-Associated Protein 2; FcR
Species:  
Source:  
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Cat. No.: HY-P84968
Synonyms: CD 16 antibody; CD 16a antibody; CD16 antibody; Fc fragment of IgG antibody; Fc fragment of IgG low affinity IIIa receptor (CD16) antibody; FcR10 antibody

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, IF-Tissue, mIHC

Reactivity:  

Human

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Cat. No.: HY-P77364
Purity:  ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: FCMR; Immunoglobulin Mu Fc Receptor; Prev. FAIM3; IgM Fc Receptor; TOSO; IgM FcR; Fas Apoptotic Inhibitory Molecule 3; IgM Fc Fragment Receptor; FcmuR; Fc Mu R; Regulator Of Fas-Induced Apoptosis Toso; Fc Mu Receptor; Fc Fragment Of IgM Receptor
Species:  
Source:  
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Cat. No.: HY-P81527
Synonyms: FCRL4; FCRH4, IFGP2, IRTA1; Fc receptor-like protein 4; CD307d; FcR-like protein 4; FcRL4; Fc receptor homolog 4 (FcRH4); IFGP family protein 2 (hIFGP2); Immune receptor translocation-associated protein 1

Host:  

Rabbit

Application:  

IHC-P

Reactivity:  

Human

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