2925302-01-6
Chemical Structure
Koshidacin B
- CAS No.: 2925302-01-6
- Formula:C28H40N4O7
- Molecular Weight:544.64
IUPAC Name: (3S,9S,14aR)-9-benzyl-3-((S)-7,8-dihydroxy-6-oxooctyl)-6,6-dimethyldecahydropyrrolo[1,2-a][1,4,7,10]tetraazacyclododecine-1,4,7,10-tetraone
InChIKey: MCPVEPXHYRIJGU-QXUYBEEESA-N
SMILES: OC[C@H](O)C(CCCCC[C@H](NC([C@H]1CCCN1C([C@@H](NC(C(C)(C)N2)=O)CC3=CC=CC=C3)=O)=O)C2=O)=O
Biological Activity: Koshidacin B is an antiplasmodial cyclic tetrapeptide with antiplasmodial activity against P. falciparum FCR3 and K1 strain with IC50 values of 0.89 and 0.83 μM, respectively. Koshidacin B suppresses malaria parasites in vivo, it can be used for the research of parasites infection[1].
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Koshidacin B | Koshidacin B is an antiplasmodial cyclic tetrapeptide with antiplasmodial activity against P. falciparum FCR3 and K1 strain with IC50 values of 0.89 and 0.83 μM, respectively. Koshidacin B suppresses malaria parasites in vivo, it can be used for the research of parasites infection. | |||||||||||||||||||||
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Keywords