1 Result for "

Fe(II)-form

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Fe(II)-form" in MCE Product Catalog:

Cat. No.: HY-128073
CAS No.: 29048-34-8
Synonyms: O-Nitrophenylfuroic acid
Target:  

Bacterial MetAP

Research Areas:  

Infection

5-(2-Nitrophenyl)-2-furoic acid (O-Nitrophenylfuroic acid) is a Mn 2+-form Escherichia coli methionine aminopeptidase (EcMetAP) inhibitor with an IC50 of 1.08 μM against Escherichia coli. 5-(2-Nitrophenyl)-2-furoic acid selectively inhibits the Mn 2+-form over the Co 2+-, Ni 2+-, and Fe 2+-forms of EcMetAP, with its carboxyl group preferentially coordinating with Mn 2+ ions as the major determinant for this metalloform selectivity. 5-(2-Nitrophenyl)-2-furoic acid can be used for the research of bacterial infection .
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