51 Results for "

FolR

" in MedChemExpress (MCE) Product Catalog:
Products (51)

51 Results for "FolR" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-132258A
CAS No.: 1453084-37-1
Pureté:  99.71%
Synonyms: IMGN853 (solution)
Domaines de recherche:  

Cancer

Mirvetuximab soravtansine (IMGN853) solution is an anti-folate receptor α (FRα) antibody drug-conjugate (ADC) consisting of the cytotoxic maytansinoid, DM4, covalently linked to the humanized monoclonal antibody M9346A, and the drug-linker conjugate for ADC is sulfo-SPDB-DM4 (HY-101141). Mirvetuximab soravtansine selectively binds to folate receptor 1 (FOLR1). Mirvetuximab soravtansine has an anti-proliferative effect via growth arrest and augmented DNA damage .
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2
2 Cited Publications
Cat. No.: HY-P99225
CAS No.: 1453084-36-0
Synonyms: M9346A

Domaines de recherche:  

Cancer

Mirvetuximab (M9346A) is an anti-FOLR1 (folate receptor 1) monoclonal antibody. Mirvetuximab is the antibody moiety of folate receptor alpha (FRα)-targeting ADC (Mirvetuximab soravtansine). Mirvetuximab soravtansine can be used in ovarian and other FRα-positive cancer research .
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2
2 Cited Publications
Cat. No.: HY-P99225A
CAS No.: 1453084-36-0
Synonyms: M9346A (powder)

Domaines de recherche:  

Cancer

Mirvetuximab (M9346A) (powder) is an anti-FOLR1 (folate receptor 1) monoclonal antibody. Mirvetuximab (powder) is the antibody moiety of folate receptor alpha (FRα)-targeting ADC (Mirvetuximab soravtansine). Mirvetuximab soravtansine can be used in ovarian and other FRα-positive cancer research .
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Cat. No.: HY-P990941
CAS No.: 2853518-94-0
Synonyms: F131; GEN1184 antibody

Target:  

Antifolate

Domaines de recherche:  

Inflammation/Immunology

Rinatabart (F131) is an IgG1-κ human antibody targeting FOLR1, with its corresponding isotype control being Human IgG1 kappa, Isotype Control (HY-P99001). The Fc region of Rinatabart is engineered to reduce antibody-dependent cellular cytotoxicity (ADCC) and complement-dependent cytotoxicity (CDC) activities. The KD values of Rinatabart binding to human FOLR1 in two sets of BLI assays are 1.528 nM and 5.296 nM, respectively. Rinatabart shows significantly lower affinity for FOLR2 and mouse FOLR1, and no reliable specific binding to FOLR3 and rat FOLR1. Rinatabart can be used in studies of FOLR1 targeting and antibody-drug conjugates .
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Cat. No.: HY-P990687

Target:  

Inhibitory Antibodies

Domaines de recherche:  

Inflammation/Immunology

Luveltamab is an anti-FOLR1 human IgG1 κ monoclonal antibody . Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-RS05029
Domaines de recherche:  

Others

FOLR1 Human Pre-designed siRNA Set A contains three designed siRNAs for FOLR1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P991695
CAS No.: 3035565-36-4

Target:  

Folate Receptor (FR)

Domaines de recherche:  

Cancer

Lazatatug is an anti-FOLR1 IgEκ type humanized antibody with antineoplastic activity .
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Cat. No.: HY-P990417

Target:  

Antifolate

Domaines de recherche:  

Inflammation/Immunology

Anti-FOLR1/FRA Antibody is a humanized antibody expressed in CHO cells, targeting FOLR1/FRA. The Anti-FOLR1/FRA Antibody contains a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 146.46 kDa. The isotype control for the Anti-FOLR1/FRA Antibody can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-RS05030
Domaines de recherche:  

Others

FOLR2 Human Pre-designed siRNA Set A contains three designed siRNAs for FOLR2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS05031
Domaines de recherche:  

Others

FOLR3 Human Pre-designed siRNA Set A contains three designed siRNAs for FOLR3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS16758
Domaines de recherche:  

Others

Folr1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Folr1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS17201
Domaines de recherche:  

Others

Folr2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Folr2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS23197
Domaines de recherche:  

Others

Folr1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Folr1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P990935
CAS No.: 2779564-38-2
Synonyms: IMGN-151 Antibody

Target:  

Antifolate

Domaines de recherche:  

Inflammation/Immunology

HY-P990935 is an FOLR1-targeting half-IG G1 -κ/(scFv -κ-heavy) -h-CH2-CH3 type chimeric antibody .
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Cat. No.: HY-P992520
Target:  

Folate Receptor (FR)

Domaines de recherche:  

Cancer

Anti-FOLR2 Antibody is a specific antibody targeting folate receptor β (FOLR2). Anti-FOLR2 Antibody effectively detects intracellular and extracellular FOLR2 expression in flow cytometry and confocal microscopy experiments, facilitating the precise detection and isolation of FOLR2+ macrophages in breast cancer. Anti-FOLR2 Antibody is also widely used in studies on the mechanisms, diagnosis and treatment of chronic lymphocytic leukemia (CLL) .
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Cat. No.: HY-RS23653
Domaines de recherche:  

Others

Folr2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Folr2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P84112
Synonyms: FBP; FolR

Host:  

Mouse

Application:  

IHC-P, ICC/IF, FC, ELISA

Reactivity:  

Human

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Cat. No.: HY-P84112A
Synonyms: FBP; FolR

Host:  

Mouse

Application:  

IHC-P, ICC/IF, FC, ELISA

Reactivity:  

Human

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Cat. No.: HY-P78871
Pureté:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: FolR1; KB Cells FBP; Prev. FolR; FBP; Ovarian Tumor-Associated Antigen MOv18; Folate Binding Protein; Adult Folate-Binding Protein; FRalpha; Folate Receptor 1 (Adult); NCFTD; Folate Receptor, Adult; FRα; Folate Receptor 1; FRA; Folate Receptor Alpha; FR-A
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P701278
Pureté:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FolR1; KB Cells FBP; Prev. FolR; FBP; Ovarian Tumor-Associated Antigen MOv18; Folate Binding Protein; Adult Folate-Binding Protein; FRalpha; Folate Receptor 1 (Adult); NCFTD; Folate Receptor, Adult; FRα; Folate Receptor 1; FRA; Folate Receptor Alpha; FR-A
Species:  
Human
Source:  
HEK293
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