Anti-FOLR2 Antibody

Anti-FOLR2 antibody detects high FOLR2 expression on protective M2-like NLCs, which correlates with enhanced in vitro survival of primary chronic lymphocytic leukemia (CLL) cells. This expression is highly prevalent in lymph nodes of CLL patients and serves as a specific marker for these supportive myeloid cells^[1].
Anti-FOLR2 antibody can detect NLC-derived FOLR2 on primary CLL cells via trogocytosis, while CLL cells themselves do not express endogenous FOLR2^[1].
Anti-FOLR2 antibody recognizes primary chronic lymphocytic leukemia (CLL) cells that acquire functional FOLR2, a protein that mediates enhanced folate uptake by cancer cells^[1].
Anti-FOLR2 antibody recognizes primary CLL cells, which represent the dominant proliferating subpopulation when co-cultured with HD-NLCs, particularly under folate-deficient conditions; their stable FOLR2 levels indicate repeated trogocytosis during cell division^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.