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Folate Binding Protein Antibody (YA3809)(PBS only)

(Synonyms: FBP; FOLR)

Folate Binding Protein Antibody (YA3809) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to Folate Binding Protein.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG2a

  • Application:

    IHC-P, ICC/IF, FC, ELISA

  • Reactivity :

    Human

  • Formulation:

    Supplied in PBS, pH 7.4.

  • Conjugation:
    Non-conjugated
  • Folate Binding Protein Antibody (YA3809)(PBS only) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
ICC/IF Info
ICC/IF: Immunocytochemistry/
Immunofluorescence
FC Info
FC: Flow Cytometry
ELISA Info
ELISA: Enzyme Linked Immunosorbent Assay
Dilution Ratio 1:200-1:1000 1:100-1:500 1:200-1:400 1:10000

Product Details

Description

Folate Binding Protein Antibody (YA3809) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to Folate Binding Protein.

  • Host Mouse
  • Species Reactivity
    Human
  • Observed Molecular Weight
    Observed band size: 40 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 30 kDa
Immunogen

Purified recombinant fragment of human FOLR1 (AA: 41-227) expressed in E. Coli.

Purification

affinity purified.

Conjugation

Non-conjugated

Isotype

IgG2a

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS, pH 7.4.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    Folate Binding Protein binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release. Required for normal embryonic development and normal cell proliferation[1][2][3][4][5][6].

  • Subcellular Localization

    Cell membrane; Lipid-anchor, GPI-anchor; Apical cell membrane; Lipid-anchor, GPI-anchor; Basolateral cell membrane; Lipid-anchor, GPI-like-anchor; Secreted; Cytoplasmic vesicle; Cytoplasmic vesicle, clathrin-coated vesicle; Endosome

  • Expression


    Tissue_specificity:It is primarily expressed in epithelial tissues. Expression increases in malignant tissues. It is expressed in the kidneys, lungs, and cerebellum. It can also be detected in the placental and thymic epithelium.

  • SwissProt ID

    P15328

  • Gene ID
    2348 [NCBI]
  • Synonyms

    FBP; FOLR

Folate Binding Protein Antibody (YA3809)(PBS only) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
  • Folate Binding Protein Antibody (YA3809)(PBS only) Product Image
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  • Folate Binding Protein Antibody (YA3809)(PBS only) Product Image