21 Results for "

GFRAL

" in MedChemExpress (MCE) Product Catalog:
Products (21)

21 Results for "GFRAL" in MCE Product Catalog:

  • Recombinant Proteins Recommended:
3
3 Cited Publications
Cat. No.: HY-P99241
CAS No.: 2368950-15-4
Synonyms: PF 06946860

Research Areas:  

Cancer

Ponsegromab is a Growth differentiation factor 15 (GDF15) inhibitor with human, cynomolgus monkey, and mouse target IC50 values of 0.123 nM, 0.053 nM, and 0.102 nM, respectively . Ponsegromab acts as a chemosensitizer, increases intracellular reactive oxygen species, reduces glutathione levels . Ponsegromab can be used for the research of oxaliplatin-resistant colorectal cancer .
loading...
    loading...
Cat. No.: HY-W587486
CAS No.: 19213-70-8
N‑acetyltaurine is an orally active endogenous sulfonate that is synthesized from taurine and acetate in the renal cortex. N‑acetyltaurine supports bacterial growth as a sole fixed nitrogen or carbon source. N‑acetyltaurine buffers acetyl moieties of mitochondrial acetyl‑CoA in skeletal muscle. N‑acetyltaurine reduces food intake and body weight in obese and lean wild‑type mice in a GFRAL‑dependent manner. N‑acetyltaurine can be used for the research of diet‑induced obesity, hyperacetatemia and diabetes .
loading...
    loading...
Cat. No.: HY-P990635

Target:  

TGF-β Receptor

Research Areas:  

Cancer

NGM-120 is a fully humanized IgG1 monoclonal antibody targeting GFRAL, which functions by blocking the GDF15-GFRAL axis. NGM-120 reduces serum GDF15 levels, increases body weight, expands central memory and proliferative CD8 + T cell populations, and decreases immunosuppressive and naive regulatory T cell populations. NGM-120 can be used for research on advanced prostate cancer .
loading...
    loading...
Cat. No.: HY-W587486R
CAS No.: 19213-70-8
N-Acetyltaurine (Standard) is the analytical standard of N-Acetyltaurine (HY-W587486). This product is intended for research and analytical applications. N‑acetyltaurine is an orally active endogenous sulfonate that is synthesized from taurine and acetate in the renal cortex. N‑acetyltaurine supports bacterial growth as a sole fixed nitrogen or carbon source. N‑acetyltaurine buffers acetyl moieties of mitochondrial acetyl‑CoA in skeletal muscle. N‑acetyltaurine reduces food intake and body weight in obese and lean wild‑type mice in a GFRAL‑dependent manner. N‑acetyltaurine can be used for the research of diet‑induced obesity, hyperacetatemia and diabetes .
loading...
    loading...
Cat. No.: HY-RS05390
Research Areas:  

Others

GFRAL Human Pre-designed siRNA Set A contains three designed siRNAs for GFRAL gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
Cat. No.: HY-RS23795
Research Areas:  

Others

Gfral Rat Pre-designed siRNA Set A contains three designed siRNAs for Gfral gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
Cat. No.: HY-RS17340
Research Areas:  

Others

Gfral Mouse Pre-designed siRNA Set A contains three designed siRNAs for Gfral gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
Cat. No.: HY-P700449
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GFR alpha-like; GFRAL; GRAL; C6orf144
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-P704634
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: GFR alpha-like; GFRAL; GRAL; C6orf144
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-P77947
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: GFR alpha-like; GFRAL; GRAL; C6orf144
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-P78449
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: GFR alpha-like; GFRAL; GRAL; C6orf144
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-P77683
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: GFR alpha-like; GFRAL; GRAL; C6orf144
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-P78135
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: GFR alpha-like; GFRAL; GRAL; C6orf144
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-P700728
Purity:  ≥ 95%, as determined by reducing Bis-Tris PAGE.
Synonyms: GFR alpha-like; GFRAL; GRAL; C6orf144
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-P700997
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GFR alpha-like; GFRAL; GRAL; C6orf144
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-P704308
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: bA360D14.1; C6orf144; GDNF family receptor alpha-like; GFRAL; GFRAL_HUMAN; GRAL; IVFI9356; UNQ9356; UNQ9356/PRO34128
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-P71580
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: bA360D14.1; C6orf144; GDNF family receptor alpha-like; GFRAL; GFRAL_HUMAN; GRAL; IVFI9356; UNQ9356; UNQ9356/PRO34128
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-P992393

Target:  

TGF-β Receptor

Research Areas:  

Cancer

JMT203 is a monoclonal antibody against GFRAL and a body weight gain inducer. JMT203 induces early-onset, sustained and progressive body weight gain in cancer cachexia. JMT203 can be used for research related to cancer cachexia .
loading...
    loading...
Cat. No.: HY-P706121
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GDNF family receptor alpha-like; GFRAL; C6orf144; UNQ9356; PRO34128
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-W587486A
CAS No.: 75350-40-2
N-Acetyltaurine hemimagnesium is an orally active endogenous sulfonate that is synthesized from taurine and acetate in the renal cortex. N-Acetyltaurine hemimagnesium supports bacterial growth as a sole fixed nitrogen or carbon source. N-Acetyltaurine hemimagnesium buffers acetyl moieties of mitochondrial acetyl‑CoA in skeletal muscle. N-Acetyltaurine hemimagnesium reduces food intake and body weight in obese and lean wild‑type mice in a GFRAL‑dependent manner. N-Acetyltaurine hemimagnesium can be used for the research of diet‑induced obesity, hyperacetatemia and diabetes .
loading...
    loading...