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Gibberella zeae

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-176552
    Tubulin polymerization-IN-83

    		Fungal Microtubule/Tubulin Infection
    Tubulin polymerization-IN-83 (Compound A23) is a flavonol derivative. Tubulin polymerization-IN-83 exhibits antifungal activity against various phytopathogenic fungi, with an EC50 of 0.338 μg/mL against Botrytis cinerea. Tubulin polymerization-IN-83 exerts its effects by targeting β-tubulin, disrupting mycelial morphology, and increasing cell membrane permeability, with relatively low ecological and environmental risks .
    Tubulin polymerization-IN-83
  • HY-183295
    Antifungal agent 160

    		Fungal Reactive Oxygen Species (ROS) Infection
    Antifungal agent 160 is a cytochrome bc1 complex inhibitor with activity against Alternaria solani, Gibberella zeae, Colletotrichum gloeosporioides, and Fusarium oxysporum f. sp. melonis. Antifungal agent 160 impairs ATP synthesis, suppresses ATPase activity, induces ROS bursts, compromises plasma membrane integrity, and suppresses fungal growth. Antifungal agent 160 can be used for the research of fungal infection .
    Antifungal agent 160
  • HY-178196
    SDH-IN-32

    		Fungal MMP Apoptosis Infection
    SDH-IN-32 is a succinate dehydrogenase (SDH) inhibitor with an IC50 of 2.74 μM. SDH-IN-32 exhibits excellent antifungal activity. SDH-IN-32 can destroy the cell membrane structure and increase the permeability of the cell membrane. SDH-IN-32 can decrease the mitochondrial membrane potential (MMP), thereby inducing cell apoptosis and inhibiting the normal growth of mycelia. SDH-IN-32 can be used for the research of infection .
    SDH-IN-32

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