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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
77 Results for "
Gly-Phe
" in MedChemExpress (MCE) Product Catalog:
Products (77)
77 Results for "Gly-Phe" in MCE Product Catalog:
4
4 Cited Publications
Cat. No.: HY-P0073
CAS No.: 58569-55-4
Synonyms: Met-Enkephalin; Methionine enkephalin; Metenkefalin
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MC-Gly-Gly-Phe-Gly is a cleavable ADC linker used for antibody-drug conjugates (ADCs).
Synonyms: SHR-A1811 Drug-linker
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MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan (SHR-A1811 Drug-linker) is a agent-linker conjugates for ADC, consisting Exatecan (HY-13631). Exatecan is a DNA Topoisomerase I inhibitor (IC50=2.2 μM) .
Cat. No.: HY-W011063
CAS No.: 21438-66-4
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Gly-Phe-β-naphthylamide is a substrate of Cathepsin C (HY-P2922) and belongs to the lysosomal agonist. Gly-Phe-β-naphthylamide can freely pass through the cell membrane and organelle membrane. Gly-Phe-β-naphthylamide will be specifically hydrolyzed by Cathepsin C, ultimately leading to a permeability lysis when it enters the acidic compartment. Gly-Phe-β-naphthylamide can be used to study lysosomal hydrolysis, lysosomal membrane permeability, and the function of cathepsin C .
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MC-Gly-Gly-Phe-Gly-PAB-PNP is a linker for synthesis anti-human EGFR antibody agent conjugate .
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MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
Cat. No.: HY-44235
CAS No.: 1599440-15-9
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MC-Gly-Gly-Phe is a cleavable linker used for antibody-drug conjugates (ADC).
Cat. No.: HY-164702
Synonyms: Izalontamab Brengitecan
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BL-B01D1 (Izalontamab Brengitecan) is a bispecific antibody-drug conjugate (ADC) targeting EGFR and HER3, formed by conjugating the EGFR/HER3 bispecific antibody Izalontamab (HY-P99676) to a novel TOP-I inhibitor payload Deruxtecan 2-hydroxypropanamide (HY-153891) via a cleavable linker (Mc-Gly-Gly-Phe-Gly). BL-B01D1 binds to EGFR and HER3 on the surface of tumor cells, mediates endocytosis and releases the payload, inhibits topoisomerase I, blocks DNA replication and RNA synthesis, and disrupts DNA structure. BL-B01D1 induces cell cycle S-phase arrest, apoptosis, antibody-dependent cell-mediated cytotoxicity, and tumor cell death. BL-B01D1 can be used for cancer research .
Cat. No.: HY-P3669
CAS No.: 200427-88-9
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Fmoc-Gly-Gly-Phe-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
Cat. No.: HY-P1449
CAS No.: 187794-49-6
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Cat. No.: HY-45672
CAS No.: 1599440-20-6
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Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is an ADC Linker that can be used to synthesize Drug-Linker Conjugates for ADC. Especially for the synthesis of Deruxtecan (HY-13631E), a toxic drug-linker conjugate .
Cat. No.: HY-P4192
CAS No.: 1817857-75-2
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Gly-Gly-Phe-Gly-NH-O-CO-Exatecan is a Drug-Linker Conjugates for ADC, consiting of an ADC linker and Exatecan (HY-13631) (topoisomerase I inhibitor). Gly-Gly-Phe-Gly-NH-O-CO-Exatecan can be used for ADC molecues synthesis.
Cat. No.: HY-177442
Synonyms: DS-3939
Synonyms: Mc-GGFG-PAB-OH
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Cat. No.: HY-45545
CAS No.: 2264011-98-3
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Fmoc-gly-gly-ph-gly-nh-ch2-o-ch2cooh can be used to synthesize the ADC Linker, LND1067 .
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Gly-Gly-Phe-Gly-NH-O-CO-Exatecan, as a drug-linker conjugate composed of linker Gly-Gly-Phe-Gly-NH-O-CO and Exatecan, can be used to prepare antibody conjugate drugs. Exatecan is a DNA topoisomerase I inhibitor that can be used in cancer research .
Cat. No.: HY-W090940
CAS No.: 6234-26-0
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H-Gly-Gly-Phe-OH is a tripeptide linker that may be used in the creation of antibody drug conjugates (ADCs). The N-terminal of the glycine tripeptide is free to perform a variety of reactions such as couplings with carboxylic acids or NHS esters.
Cat. No.: HY-W013998
CAS No.: 3321-03-7
Synonyms: Gly-Phe; H-Gly-Phe-OH
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
