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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
HDAC ligand1
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "HDAC ligand1" in MCE Product Catalog:
Cat. No.: HY-150859
CAS No.: 34840-28-3
Research Areas:
HDAC ligand-1 is a HDAC ligand that can be used to synthesize PROTAC HDAC degraders, such as compounds 21a and 21b in references .
Cat. No.: HY-168287
Research Areas:
HDAC3/8 ligand-1 (compound 40) is a ligand for target protein for PROTAC that can be used in the synthesis of YX968 (HY-164233) .
Cat. No.: HY-187388
Research Areas:
HDAC6/ERα ligand-1 is a dual-target ligand with inhibitory activity against both estrogen receptor α (ERα) and histone deacetylase 6 (HDAC6). HDAC6/ERα ligand-1 can be used to synthesize PROTACs, such as PROTAC HDAC6/ERα degrader 1 (HY-187387). HDAC6/ERα ligand-1 binds to the ligand-binding pocket of ERα and forms hydrogen bonds with specific residues in helices 10, 11 and 12. HDAC6/ERα ligand-1 binds stably to HDAC6 and forms hydrogen bonds with specific residues of this protein. HDAC6/ERα ligand-1 can be used in breast cancer research .
Cat. No.: HY-168176
Research Areas:
HDAC8 ligand 1 is a PROTAC target protein-ligand of PROTAC HDAC8 Degrader-2 (HY-168174) .
Cat. No.: HY-187389
CAS No.: 3092712-04-1
Research Areas:
HDAC6/ERα ligand-1-C6-COOH is a conjugate of a target protein ligand (HY-187387) and a linker. HDAC6/ERα ligand-1-C6-COOH serves as an intermediate in the synthesis of ERα/HDAC6 dual-target PROTACs, and can be used for the synthesis of PROTAC molecules .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
